Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA

by Lin Chen, Yibin Xu, Wilson Wong, Jennifer K Thompson, Julie Healer, Ethan D Goddard-Borger, Michael C Lawrence, Alan F Cowman
Published 2017-02-01

Protein Kinase A Is Essential for Invasion of Plasmodium falciparum into Human Erythrocytes

by Mary-Louise Wilde, Tony Triglia, Danushka Marapana, Jennifer K. Thompson, Alexei A. Kouzmitchev, Hayley E. Bullen, Paul R. Gilson, Alan F. Cowman, Christopher J. Tonkin
Published 2019-10-01

Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum.

by Julie Healer, Jennifer K Thompson, David T Riglar, Danny W Wilson, Yu-H C Chiu, Kazutoyo Miura, Lin Chen, Anthony N Hodder, Carole A Long, Diana S Hansen, Jake Baum, Alan F Cowman
Published 2013-01-01

Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion

by Xavier Sisquella, Thomas Nebl, Jennifer K Thompson, Lachlan Whitehead, Brian M Malpede, Nichole D Salinas, Kelly Rogers, Niraj H Tolia, Andrea Fleig, Joseph O’Neill, Wai-Hong Tham, F David Horgen, Alan F Cowman
Published 2017-02-01

4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation

by Niall D. Geoghegan, Cindy Evelyn, Lachlan W. Whitehead, Michal Pasternak, Phoebe McDonald, Tony Triglia, Danushka S. Marapana, Daryan Kempe, Jennifer K. Thompson, Michael J. Mlodzianoski, Julie Healer, Maté Biro, Alan F. Cowman, Kelly L. Rogers
Published 2021-06-01

Association of antibodies to Plasmodium falciparum Reticulocyte Binding Protein Homologue 5 with protection from clinical malaria

by Chris Y. H. Chiu, Chris Y. H. Chiu, Julie eHealer, Jennifer K. Thompson, Lin eChen, Aiki eKaul, Laxman eSavergave, Arjun eRaghuwanshi, Connie S. N, Li Wai Suen, Peter M. Siba, Louis eSchofield, Louis eSchofield, Ivo eMueller, Ivo eMueller, Alan F Cowman, Alan F Cowman, Diana Silvia Hansen, Diana Silvia Hansen
Published 2014-06-01

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

by Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Published 2020-04-01