Utilisation of the Prestwick Chemical Library to identify drugs that inhibit the growth of mycobacteria.

by Panchali Kanvatirth, Rose E Jeeves, Joanna Bacon, Gurdyal S Besra, Luke J Alderwick
Published 2019-01-01

Optimisation of <i>Mycobacterium bovis</i> BCG Fermentation and Storage Survival

by Jordan Pascoe, Charlotte L. Hendon-Dunn, Colin P.D. Birch, Gareth A. Williams, Mark A. Chambers, Joanna Bacon
Published 2020-09-01

Noncytotoxic Pyrrolobenzodiazepine–Ciprofloxacin Conjugate with Activity against Mycobacterium tuberculosis

by Pietro Picconi, Rose Jeeves, Christopher William Moon, Shirin Jamshidi, Kazi S. Nahar, Mark Laws, Joanna Bacon, Khondaker Miraz Rahman
Published 2019-12-01

Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix.

by Joanna Bacon, Luke J Alderwick, Jon A Allnutt, Evelina Gabasova, Robert Watson, Kim A Hatch, Simon O Clark, Rose E Jeeves, Alice Marriott, Emma Rayner, Howard Tolley, Geoff Pearson, Graham Hall, Gurdyal S Besra, Lorenz Wernisch, Ann Williams, Philip D Marsh
Published 2014-01-01

Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315.

by Rose E Jeeves, Alice A N Marriott, Steven T Pullan, Kim A Hatch, Jon C Allnutt, Irene Freire-Martin, Charlotte L Hendon-Dunn, Robert Watson, Adam A Witney, Richard H Tyler, Catherine Arnold, Philip D Marsh, Timothy D McHugh, Joanna Bacon
Published 2015-01-01

Bioreactor-Grown Bacillus of Calmette and Guérin (BCG) Vaccine Protects Badgers against Virulent <i>Mycobacterium bovis</i> When Administered Orally: Identifying Limitations in Bai...

by Sandrine Lesellier, Colin P. D. Birch, Dipesh Davé, Deanna Dalley, Sonya Gowtage, Simonette Palmer, Claire McKenna, Gareth A. Williams, Roland Ashford, Ute Weyer, Sarah Beatham, Julia Coats, Alex Nunez, Pedro Sanchez-Cordon, John Spiropoulos, Stephen Powell, Jason Sawyer, Jordan Pascoe, Charlotte Hendon-Dunn, Joanna Bacon, Mark A. Chambers
Published 2020-08-01

Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection

by Charlotte Manisty, Thomas Alexander Treibel, Melanie Jensen, Amanda Semper, George Joy, Rishi K Gupta, Teresa Cutino-Moguel, Mervyn Andiapen, Jessica Jones, Stephen Taylor, Ashley Otter, Corrina Pade, Joseph Gibbons, Jason Lee, Joanna Bacon, Steve Thomas, Chris Moon, Meleri Jones, Dylan Williams, Jonathan Lambourne, Marianna Fontana, Daniel M Altmann, Rosemary Boyton, Mala Maini, Aine McKnight, Benjamin Chain, Mahdad Noursadeghi, James C Moon
Published 2021-03-01