COVID‐19 hypothesis: Activated protein C for therapy of virus‐induced pathologic thromboinflammation

by John H. Griffin, Patrick Lyden
Published 2020-05-01

Serum amyloid A4 is a procoagulant apolipoprotein that it is elevated in venous thrombosis patients

by José A. Fernández, Hiroshi Deguchi, Darlene J. Elias, John H. Griffin
Published 2020-02-01

Lyso-Sulfatide Binds Factor Xa and Inhibits Thrombin Generation by the Prothrombinase Complex.

by Subramanian Yegneswaran, Yajnavalka Banerjee, José A Fernández, Hiroshi Deguchi, John H Griffin
Published 2015-01-01

Activated Protein C Attenuates Experimental Autoimmune Encephalomyelitis Progression by Enhancing Vascular Integrity and Suppressing Microglial Activation

by Ravi Kant, Sebok K. Halder, Jose A. Fernández, John H. Griffin, Richard Milner
Published 2020-04-01

An engineered factor Va prevents bleeding induced by anticoagulant wt activated protein C.

by Annette von Drygalski, Vikas Bhat, Andrew J Gale, Laurent Burnier, Thomas J Cramer, John H Griffin, Laurent O Mosnier
Published 2014-01-01

Stroke Treatment With PAR-1 Agents to Decrease Hemorrhagic Transformation

by Patrick D. Lyden, Kent E. Pryor, Jennifer Minigh, Thomas P. Davis, John H. Griffin, Howard Levy, Berislav V. Zlokovic
Published 2021-03-01

Activated Protein C (APC) and 3K3A-APC-Induced Regression of Choroidal Neovascularization (CNV) Is Accompanied by Vascular Endothelial Growth Factor (VEGF) Reduction

by Tami Livnat, Yehonatan Weinberger, José A Fernández, Alaa Bashir, Gil Ben-David, Dahlia Palevski, Sarina Levy-Mendelovich, Gili Kenet, Ivan Budnik, Yael Nisgav, John H. Griffin, Dov Weinberger
Published 2021-02-01

Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin.

by Vijayalakshmi Sridharan, Kristin A Johnson, Reid D Landes, Maohua Cao, Preeti Singh, Gail Wagoner, Abdallah Hayar, Emily D Sprick, Kayla A Eveld, Anusha Bhattacharyya, Kimberly J Krager, Nukhet Aykin-Burns, Hartmut Weiler, Jose A Fernández, John H Griffin, Marjan Boerma
Published 2021-01-01