Drug development: The cell wall as a drug target

by Jonathan A.G Cox
Published 2016-01-01

Modelling a Silent Epidemic: A Review of the In Vitro Models of Latent Tuberculosis

by Savannah E.R. Gibson, James Harrison, Jonathan A.G. Cox
Published 2018-11-01

<i>Mycobacterium abscessus</i>: Environmental Bacterium Turned Clinical Nightmare

by Rose C. Lopeman, James Harrison, Maya Desai, Jonathan A. G. Cox
Published 2019-03-01

Clinical Significance of Manuka and Medical-Grade Honey for Antibiotic-Resistant Infections: A Systematic Review

by Victoria C. Nolan, James Harrison, John E. E. Wright, Jonathan A. G. Cox
Published 2020-10-01

Aston University's Antimicrobial Resistance (AMR) Roadshow: raising awareness and embedding knowledge of AMR in key stage 4 learners

by Rabia Ahmed, Amreen Bashir, James E.P. Brown, Jonathan A.G. Cox, Anthony C. Hilton, Samantha L. Jordan, Eirini Theodosiou, Tony Worthington
Published 2020-06-01

Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline

by Christopher Burke, Monika Jankute, Patrick Moynihan, Ruben Gonzalez del Rio, Xiaojun Li, Jorge Esquivias, Joël Lelièvre, Jonathan A. G. Cox, James Sacchettini, Gurdyal S. Besra
Published 2020-10-01

Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets

by Valentin Trofimov, Sébastien Kicka, Sabrina Mucaria, Nabil Hanna, Fernando Ramon-Olayo, Laura Vela-Gonzalez Del Peral, Joël Lelièvre, Lluís Ballell, Leonardo Scapozza, Gurdyal S. Besra, Jonathan A. G. Cox, Thierry Soldati
Published 2018-03-01

Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation.

by Grace Mugumbate, Katherine A Abrahams, Jonathan A G Cox, George Papadatos, Gerard van Westen, Joël Lelièvre, Szymon T Calus, Nicholas J Loman, Lluis Ballell, David Barros, John P Overington, Gurdyal S Besra
Published 2015-01-01

Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB.

by Katherine A Abrahams, Jonathan A G Cox, Vickey L Spivey, Nicholas J Loman, Mark J Pallen, Chrystala Constantinidou, Raquel Fernández, Carlos Alemparte, Modesto J Remuiñán, David Barros, Lluis Ballell, Gurdyal S Besra
Published 2012-01-01

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target.

by Sudagar S Gurcha, Veeraraghavan Usha, Jonathan A G Cox, Klaus Fütterer, Katherine A Abrahams, Apoorva Bhatt, Luke J Alderwick, Robert C Reynolds, Nicholas J Loman, VijayaShankar Nataraj, Carlos Alemparte, David Barros, Adrian J Lloyd, Lluis Ballell, Judith V Hobrath, Gurdyal S Besra
Published 2014-01-01

Identification of KasA as the cellular target of an anti-tubercular scaffold

by Katherine A. Abrahams, Chun-wa Chung, Sonja Ghidelli-Disse, Joaquín Rullas, María José Rebollo-López, Sudagar S. Gurcha, Jonathan A. G. Cox, Alfonso Mendoza, Elena Jiménez-Navarro, María Santos Martínez-Martínez, Margarete Neu, Anthony Shillings, Paul Homes, Argyrides Argyrou, Ruth Casanueva, Nicholas J. Loman, Patrick J. Moynihan, Joël Lelièvre, Carolyn Selenski, Matthew Axtman, Laurent Kremer, Marcus Bantscheff, Iñigo Angulo-Barturen, Mónica Cacho Izquierdo, Nicholas C. Cammack, Gerard Drewes, Lluis Ballell, David Barros, Gurdyal S. Besra, Robert H. Bates
Published 2016-09-01