Neuroinflammation: Microglia and T Cells Get Ready to Tango

by Sjoerd T. T. Schetters, Diego Gomez-Nicola, Juan J. Garcia-Vallejo, Yvette Van Kooyk
Published 2018-01-01

Interaction of polysialic acid with CCL21 regulates the migratory capacity of human dendritic cells.

by Marieke Bax, Sandra J van Vliet, Manja Litjens, Juan J García-Vallejo, Yvette van Kooyk
Published 2009-09-01

Immune involvement of the contralateral hemisphere in a glioblastoma mouse model

by Matheus H W Crommentuijn, Sjoerd T T Schetters, Sophie A Dusoswa, Laura J W Kruijssen, Juan J Garcia-Vallejo, Yvette van Kooyk
Published 2020-06-01

Interaction of the capsular polysaccharide A from Bacteroides fragilis with DC-SIGN on human dendritic cells is necessary for its processing and presentation to T cells.

by Karien eBloem, Karien eBloem, Juan J Garcia-Vallejo, Ilona M Vuist, Brian eCobb, Sandra J van Vliet, Yvette eVan Kooyk
Published 2013-05-01

Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I

by Sophie K. Horrevorts, Sanne Duinkerken, Karien Bloem, Karien Bloem, Pablo Secades, Hakan Kalay, René J. Musters, Sandra J. van Vliet, Juan J. García-Vallejo, Yvette van Kooyk
Published 2018-06-01

Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain.

by Karien Bloem, Ilona M Vuist, Arend-Jan van der Plas, Léon M J Knippels, Johan Garssen, Juan J García-Vallejo, Sandra J van Vliet, Yvette van Kooyk
Published 2013-01-01

Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells

by Sophie A. Dusoswa, Sophie K. Horrevorts, Martino Ambrosini, Hakan Kalay, Nanne J. Paauw, Rienk Nieuwland, Michiel D. Pegtel, Tom Würdinger, Yvette Van Kooyk, Juan J. Garcia-Vallejo
Published 2019-12-01

Phenotypic and Functional Properties of Human Steady State CD14+ and CD1a+ Antigen Presenting Cells and Epidermal Langerhans Cells.

by Cynthia M Fehres, Sven C M Bruijns, Brigit N Sotthewes, Hakan Kalay, Lana Schaffer, Steven R Head, Tanja D de Gruijl, Juan J Garcia-Vallejo, Yvette van Kooyk
Published 2015-01-01

Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity

by Sjoerd T. T. Schetters, Laura J. W. Kruijssen, Matheus H. W. Crommentuijn, Hakan Kalay, Jordi Ochando, Jordi Ochando, Joke M. M. den Haan, Juan J. Garcia-Vallejo, Yvette van Kooyk
Published 2018-05-01

Glycan modification of antigen alters its intracellular routing in dendritic cells, promoting priming of T cells

by Ingeborg Streng-Ouwehand, Nataschja I Ho, Manja Litjens, Hakan Kalay, Martine Annemarie Boks, Lenneke AM Cornelissen, Satwinder Kaur Singh, Eirikur Saeland, Juan J Garcia-Vallejo, Ferry A Ossendorp, Wendy WJ Unger, Yvette van Kooyk
Published 2016-03-01

Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation

by Juan M. Ilarregui, Gijs Kooij, Ernesto Rodríguez, Susanne M. A. van der Pol, Nathalie Koning, Hakan Kalay, Joost C. van der Horst, Sandra J. van Vliet, Juan J. García-Vallejo, Helga E. de Vries, Yvette van Kooyk
Published 2019-06-01

Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration

by Melissa A Lopes Pinheiro, Alwin Kamermans, Juan J Garcia-Vallejo, Bert van het Hof, Laura Wierts, Tom O'Toole, Daniël Boeve, Marleen Verstege, Susanne MA van der Pol, Yvette van Kooyk, Helga E de Vries, Wendy WJ Unger
Published 2016-06-01

The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10.

by Louis S Ates, Aniek D van der Woude, Jovanka Bestebroer, Gunny van Stempvoort, René J P Musters, Juan J Garcia-Vallejo, Daisy I Picavet, Robert van de Weerd, Massimiliano Maletta, Coenraad P Kuijl, Nicole N van der Wel, Wilbert Bitter
Published 2016-06-01

Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition

by Dorian A. Stolk, Sophie K. Horrevorts, Sjoerd T.T. Schetters, Laura J.W. Kruijssen, Sanne Duinkerken, Eelco Keuning, Martino Ambrosini, Hakan Kalay, Rieneke van de Ven, Juan J. Garcia-Vallejo, Tanja D. de Gruijl, Sandra J. van Vliet, Yvette van Kooyk
Published 2021-06-01

The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

by Roxan F.C.P.A. Helderman, Daan R. Löke, Jan Verhoeff, Hans M. Rodermond, Gregor G.W. van Bochove, Menno Boon, Sanne van Kesteren, Juan J. Garcia Vallejo, H. Petra Kok, Pieter J. Tanis, Nicolaas A.P. Franken, Johannes Crezee, Arlene L. Oei
Published 2020-07-01

Ipilimumab plus nivolumab and chemoradiotherapy followed by surgery in patients with resectable and borderline resectable T3-4N0–1 non-small cell lung cancer: the INCREASE trial

by Chris Dickhoff, Suresh Senan, Famke L. Schneiders, Joris Veltman, Sayed Hashemi, Johannes M. A. Daniels, Marieke Fransen, David J. Heineman, Teodora Radonic, Peter M. van de Ven, Imke H. Bartelink, Lilian J. Meijboom, Juan J. Garcia-Vallejo, Daniela E. Oprea-Lager, Tanja D. de Gruijl, Idris Bahce
Published 2020-08-01

Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9

by Ernesto Rodriguez, Kelly Boelaars, Kari Brown, R. J. Eveline Li, Laura Kruijssen, Sven C. M. Bruijns, Thomas van Ee, Sjoerd T. T. Schetters, Matheus H. W. Crommentuijn, Joost C. van der Horst, Nicole C. T. van Grieken, Sandra J. van Vliet, Geert Kazemier, Elisa Giovannetti, Juan J. Garcia-Vallejo, Yvette van Kooyk
Published 2021-02-01

Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming

by Dieke van Dinther, Henrike Veninga, Salvador Iborra, Ellen G.F. Borg, Leoni Hoogterp, Katarzyna Olesek, Marieke R. Beijer, Sjoerd T.T. Schetters, Hakan Kalay, Juan J. Garcia-Vallejo, Kees L. Franken, Lamin B. Cham, Karl S. Lang, Yvette van Kooyk, David Sancho, Paul R. Crocker, Joke M.M. den Haan
Published 2018-02-01

Glycan-Modified Apoptotic Melanoma-Derived Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination

by Sophie K. Horrevorts, Dorian A. Stolk, Rieneke van de Ven, Myrthe Hulst, Bert van Het Hof, Sanne Duinkerken, Marieke H. Heineke, Wenbin Ma, Sophie A. Dusoswa, Rienk Nieuwland, Juan J. Garcia-Vallejo, Arjan A. van de Loosdrecht, Tanja D. de Gruijl, Sandra J. van Vliet, Yvette van Kooyk
Published 2019-08-01

Galectin-2 induces a proinflammatory, anti-arteriogenic phenotype in monocytes and macrophages.

by Cansu Yıldırım, Daphne Y S Vogel, Maurits R Hollander, Josefien M Baggen, Ruud D Fontijn, Sylvia Nieuwenhuis, Anouk Haverkamp, Margreet R de Vries, Paul H A Quax, Juan J Garcia-Vallejo, Anja M van der Laan, Christine D Dijkstra, Tineke C T M van der Pouw Kraan, Niels van Royen, Anton J G Horrevoets
Published 2015-01-01