A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.

by Danielle A Simmons, Juliet K Knowles, Nadia P Belichenko, Gargi Banerjee, Carly Finkle, Stephen M Massa, Frank M Longo
Published 2014-01-01

Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment.

by Tao Yang, Juliet K Knowles, Qun Lu, Hong Zhang, Ottavio Arancio, Laura A Moore, Timothy Chang, Qian Wang, Katrin Andreasson, Jayakumar Rajadas, Gerald G Fuller, Youmei Xie, Stephen M Massa, Frank M Longo
Published 2008-01-01