Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies

by Tao Yang, Kevin C. Tran, Anne Y. Zeng, Stephen M. Massa, Frank M. Longo
Published 2020-11-01

Small-molecule modulation of the p75 neurotrophin receptor inhibits a wide range of tau molecular pathologies and their sequelae in P301S tauopathy mice

by Tao Yang, Harry Liu, Kevin C. Tran, Albert Leng, Stephen M. Massa, Frank M. Longo
Published 2020-09-01

A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.

by Danielle A Simmons, Juliet K Knowles, Nadia P Belichenko, Gargi Banerjee, Carly Finkle, Stephen M Massa, Frank M Longo
Published 2014-01-01

Bioenergetic state regulates innate inflammatory responses through the transcriptional co-repressor CtBP

by Yiguo Shen, David Kapfhamer, Angela M. Minnella, Ji-Eun Kim, Seok Joon Won, Yanting Chen, Yong Huang, Ley Hian Low, Stephen M. Massa, Raymond A. Swanson
Published 2017-09-01

Nerve Growth Factor Pathobiology During the Progression of Alzheimer’s Disease

by Elliott J. Mufson, Scott E. Counts, Stephen D. Ginsberg, Stephen D. Ginsberg, Laura Mahady, Sylvia E. Perez, Stephen M. Massa, Frank M. Longo, Milos D. Ikonomovic
Published 2019-07-01

Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment.

by Tao Yang, Juliet K Knowles, Qun Lu, Hong Zhang, Ottavio Arancio, Laura A Moore, Timothy Chang, Qian Wang, Katrin Andreasson, Jayakumar Rajadas, Gerald G Fuller, Youmei Xie, Stephen M Massa, Frank M Longo
Published 2008-01-01