Regulation of Antitumor Immune Responses by the IL-12 Family Cytokines, IL-12, IL-23, and IL-27

by Mingli Xu, Izuru Mizoguchi, Noriko Morishima, Yukino Chiba, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2010-01-01

IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner.

by Yukino Chiba, Izuru Mizoguchi, Kana Mitobe, Kaname Higuchi, Hiroshi Nagai, Chikako Nishigori, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2013-01-01

Suppressive effects of a novel compound on interphotoreceptor retinoid-binding protein-induced experimental autoimmune uveoretinitis in rats

by Jun-ichi Sakai, Takeshi Kezuka, Hidetoshi Yokoi, Annabelle A Okada, Masahiko Usui, Junichiro Mizuguchi, Yutaro Kaneko
Published 1999-01-01

A Pivotal Role for Interleukin-27 in CD8+ T Cell Functions and Generation of Cytotoxic T Lymphocytes

by Noriko Morishima, Izuru Mizoguchi, Masae Okumura, Yukino Chiba, Mingli Xu, Motomu Shimizu, Masanori Matsui, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2010-01-01

Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases

by Ning Qu, Mingli Xu, Izuru Mizoguchi, Jun-ichi Furusawa, Kotaro Kaneko, Kazunori Watanabe, Junichiro Mizuguchi, Masahiro Itoh, Yutaka Kawakami, Takayuki Yoshimoto
Published 2013-01-01

Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis.

by Jun-ichi Furusawa, Izuru Mizoguchi, Yukino Chiba, Masayuki Hisada, Fumie Kobayashi, Hiroki Yoshida, Susumu Nakae, Akihiko Tsuchida, Tetsuya Matsumoto, Hideo Ema, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2016-03-01