Role of Interleukin-33 in Innate-Type Immune Cells in Allergy

by Susumu Nakae, Hideaki Morita, Tatsukuni Ohno, Ken Arae, Kenji Matsumoto, Hirohisa Saito
Published 2013-01-01

Regulatory T Cells Exhibit Interleukin-33-Dependent Migratory Behavior during Skin Barrier Disruption

by Sumika Toyama, Catharina Sagita Moniaga, Susumu Nakae, Masaru Kurosawa, Hideoki Ogawa, Mitsutoshi Tominaga, Kenji Takamori
Published 2021-07-01

Cimetidine Enhances Antigen-Specific IgE and Th2 Cytokine Production

by Ken Arae, Keisuke Oboki, Tatsukuni Ohno, Masako Hirata, Susumu Nakae, Haruhiko Taguchi, Hirohisa Saito, Toshiharu Nakajima
Published 2011-01-01

Role of Regulatory and Proinflammatory T-Cell Populations in Allergic Diseases

by Kanami Orihara, PhD, Susumu Nakae, PhD, Ruby Pawankar, MD, PhD, Hirohisa Saito, MD, PhD
Published 2008-01-01

Innate Lymphoid Cells in the Induction of Obesity

by Takaharu Sasaki, Kazuyo Moro, Tetsuya Kubota, Naoto Kubota, Tamotsu Kato, Hiroshi Ohno, Susumu Nakae, Hirohisa Saito, Shigeo Koyasu
Published 2019-07-01

The optimal age for epicutaneous sensitization following tape-stripping in BALB/c mice

by Masato Tamari, Keisuke Orimo, Kenichiro Motomura, Ken Arae, Akio Matsuda, Susumu Nakae, Hirohisa Saito, Hideaki Morita, Kenji Matsumoto
Published 2018-07-01

Human eosinophils constitutively express a unique serine protease, PRSS33

by Sumika Toyama, Naoko Okada, Akio Matsuda, Hideaki Morita, Hirohisa Saito, Takao Fujisawa, Susumu Nakae, Hajime Karasuyama, Kenji Matsumoto
Published 2017-07-01

Role of interleukin-25 in development of spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice

by Yasuharu Abe, Aya Nambu, Sachiko Yamaguchi, Ayako Takamori, Hajime Suto, Sachiko Hirose, Tadashi Yokosuka, Susumu Nakae, Katsuko Sudo
Published 2017-12-01

IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release.

by Julia Siede, Anja Fröhlich, Angeliki Datsi, Ahmed N Hegazy, Domonkos V Varga, Vivien Holecska, Hirohisa Saito, Susumu Nakae, Max Löhning
Published 2016-01-01

Alteration of Immune Responses by N-acetylglucosaminyltransferase V during Allergic Airway Inflammation

by Akiko Shibui, Aya Nambu, Eri Shimura, Sachiko Yamaguchi, Chiharu Shiraishi, Yoshitaka Sato, Ko Okumura, Sumio Sugano, Nobumichi Hozumi, Susumu Nakae
Published 2011-01-01

Amphiregulin is Not Essential for Induction of Contact Hypersensitivity

by Akiko Yagami, Naoki Kajiwara, Keisuke Oboki, Tatsukuni Ohno, Hideaki Morita, Susan W Sunnarborg, Ko Okumura, Hideoki Ogawa, Hirohisa Saito, Susumu Nakae
Published 2010-01-01

Development of IL-17-mediated Delayed-Type Hypersensitivity Is Not Affected by Down-Regulation of IL-25 Expression

by Akina Ishii, Keisuke Oboki, Aya Nambu, Hideaki Morita, Tatsukuni Ohno, Naoki Kajiwara, Ken Arae, Hajime Sudo, Ko Okumura, Hirohisa Saito, Susumu Nakae
Published 2010-01-01

Galectin-9 enhances cytokine secretion, but suppresses survival and degranulation, in human mast cell line.

by Reiji Kojima, Tatsukuni Ohno, Motoyasu Iikura, Toshiro Niki, Mitsuomi Hirashima, Keichi Iwaya, Hitoshi Tsuda, Shigeaki Nonoyama, Akio Matsuda, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae
Published 2014-01-01

IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis.

by Wakako Nakanishi, Sachiko Yamaguchi, Akira Matsuda, Maho Suzukawa, Akiko Shibui, Aya Nambu, Kenji Kondo, Hajime Suto, Hirohisa Saito, Kenji Matsumoto, Tatuya Yamasoba, Susumu Nakae
Published 2013-01-01

Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity.

by Atsushi Otsuka, Masato Kubo, Tetsuya Honda, Gyohei Egawa, Saeko Nakajima, Hideaki Tanizaki, Bongju Kim, Satoshi Matsuoka, Takeshi Watanabe, Susumu Nakae, Yoshiki Miyachi, Kenji Kabashima
Published 2011-01-01

ST2 Requires Th2-, but Not Th17-, Type Airway Inflammation in Epicutaneously Antigen-Sensitized Mice

by Hideaki Morita, Ken Arae, Tatsukuni Ohno, Naoki Kajiwara, Keisuke Oboki, Akio Matsuda, Hajime Suto, Ko Okumura, Katsuko Sudo, Takao Takahashi, Kenji Matsumoto, Susumu Nakae
Published 2012-01-01

Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis.

by Jun-ichi Furusawa, Izuru Mizoguchi, Yukino Chiba, Masayuki Hisada, Fumie Kobayashi, Hiroki Yoshida, Susumu Nakae, Akihiko Tsuchida, Tetsuya Matsumoto, Hideo Ema, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2016-03-01

IL-25 and IL-33 Contribute to Development of Eosinophilic Airway Inflammation in Epicutaneously Antigen-Sensitized Mice.

by Hideaki Morita, Ken Arae, Hirotoshi Unno, Sumika Toyama, Kenichiro Motomura, Akio Matsuda, Hajime Suto, Ko Okumura, Katsuko Sudo, Takao Takahashi, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae
Published 2015-01-01

TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens

by Yoshihisa Hiraishi, Aya Nambu, Akiko Shibui, Wakako Nakanishi, Sachiko Yamaguchi, Hideaki Morita, Motoyasu Iikura, Andrew N.J. McKenzie, Kenji Matsumoto, Katsuko Sudo, Tatsuya Yamasoba, Takahide Nagase, Susumu Nakae
Published 2016-10-01

Interleukin-33 and thymic stromal lymphopoietin, but not interleukin-25, are crucial for development of airway eosinophilia induced by chitin

by Ken Arae, Masashi Ikutani, Kotaro Horiguchi, Sachiko Yamaguchi, Youji Okada, Hiroki Sugiyama, Keisuke Orimo, Hideaki Morita, Hajime Suto, Ko Okumura, Haruhiko Taguchi, Kenji Matsumoto, Hirohisa Saito, Katsuko Sudo, Susumu Nakae
Published 2021-03-01