A Nonpolycationic Fully Proteinaceous Multiagent System for Potent Targeted Delivery of siRNA

by David V Liu, Nicole J Yang, K Dane Wittrup
Published 2014-01-01

Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models

by Adrienne Rothschilds, Alice Tzeng, Naveen K. Mehta, Kelly D. Moynihan, Darrell J. Irvine, K. Dane Wittrup
Published 2019-05-01

Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis

by Alessandro Angelini, Yoshishige Miyabe, Daniel Newsted, Byron H. Kwan, Chie Miyabe, Ryan L. Kelly, Misha N. Jamy, Andrew D. Luster, K. Dane Wittrup
Published 2018-04-01

An engineered protein antagonist of K-Ras/B-Raf interaction

by Monique J. Kauke, Michael W. Traxlmayr, Jillian A. Parker, Jonathan D. Kiefer, Ryan Knihtila, John McGee, Greg Verdine, Carla Mattos, K. Dane Wittrup
Published 2017-07-01

Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma

by Didier Dréau, Laura Jeffords Moore, Mike Wu, Lopa Das Roy, Lloye Dillion, Travis Porter, Rahul Puri, Noor Momin, K. Dane Wittrup, Pinku Mukherjee, Pinku Mukherjee
Published 2019-04-01

Engineering protein-based modulators of allergic, temporal, and checkpoint blockade anti-cancer immunity

by Rothschilds, Adrienne Marie.
Published 2019

New protein engineering approaches for potentiating and studying antibody-based EGFR antagonism

by Tisdale, Alison Wedekind.
Published 2019

Engineering persistent interleukin-2 for cancer immunotherapy

by Gai, Shuning
Published 2013

Synergistic anti-tumor immune response to combination immunotherapy consisting of anti-tumor antibodies, extended half-life Interleukin-2, and other immunomodulatory agents

by Zhu, Eric F. (Eric Franklin)
Published 2017

Characterization and informed design of downregulating anti-epidermal growth factor receptor antibodies

by Spangler, Jamie Berta
Published 2013

T cell mediated combination immunotherapy

by Opel, Cary F. (Cary Francis)
Published 2017

Engineering therapeutic proteins for immune modulation

by Chen, Tiffany F. (Tiffany Fen-yi)
Published 2014

Antibody engineering for tumor immunotherapy

by Graff, Christilyn Paula
Published 2005

Targeting immunosuppression in the tumor microenvironment and protein-based antagonism of oncogenic K-Ras

by Kauke, Monique Jacqueline
Published 2018

Biophysical characterization of high affinity engineered single chain Fv antibody fragments

by Midelfort, Katarina Senn
Published 2006

Yeast-based vaccine approaches to cancer immunotherapy

by Howland, Shanshan W
Published 2009

Antibody engineering for cancer therapy

by Yeung, Yik Andy
Published 2006

Reversibly neutralized perfringolysin O for intracellular delivery of macromolecules/

by Yang, Nicole J. (Nicole Jieyeon)
Published 2016

Protein engineering for targeted delivery of radionuclides to tumors

by Orcutt, Kelly Davis
Published 2010

Quantitative analysis of perivascular antibody distribution in solid tumors

by Rhoden, John J. (John Joseph)
Published 2013