How the venom from the ectoparasitoid Wasp nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines.

by Ellen L Danneels, Sarah Gerlo, Karen Heyninck, Kathleen Van Craenenbroeck, Karolien De Bosscher, Guy Haegeman, Dirk C de Graaf
Published 2014-01-01

Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells.

by Ajay Palagani, Ken Op de Beeck, Stefan Naulaerts, Jolien Diddens, Chandra Sekhar Chirumamilla, Guy Van Camp, Kris Laukens, Karen Heyninck, Sarah Gerlo, Pieter Mestdagh, Joke Vandesompele, Wim Vanden Berghe
Published 2014-01-01

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.

by Katarzyna Szarc vel Szic, Ken Op de Beeck, Dariusz Ratman, An Wouters, Ilse M Beck, Ken Declerck, Karen Heyninck, Erik Fransen, Marc Bracke, Karolien De Bosscher, Filip Lardon, Guy Van Camp, Wim Vanden Berghe
Published 2014-01-01

Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease

by Geoffrey Istas, Ken Declerck, Maria Pudenz, Katarzyna Szarc vel Szic, Veronica Lendinez-Tortajada, Montserrat Leon-Latre, Karen Heyninck, Guy Haegeman, Jose A. Casasnovas, Maria Tellez-Plaza, Clarissa Gerhauser, Christian Heiss, Ana Rodriguez-Mateos, Wim Vanden Berghe
Published 2017-07-01

Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.

by Dragan Milenkovic, Wim Vanden Berghe, Céline Boby, Christine Leroux, Ken Declerck, Katarzyna Szarc vel Szic, Karen Heyninck, Kris Laukens, Martin Bizet, Matthieu Defrance, Sarah Dedeurwaerder, Emilie Calonne, Francois Fuks, Guy Haegeman, Guido R M M Haenen, Aalt Bast, Antje R Weseler
Published 2014-01-01