Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy

by Marc Baay, Anja Brouwer, Patrick Pauwels, Marc Peeters, Filip Lardon
Published 2011-01-01

Immune Checkpoint Modulation in Colorectal Cancer: What’s New and What to Expect

by Julie Jacobs, Evelien Smits, Filip Lardon, Patrick Pauwels, Vanessa Deschoolmeester
Published 2015-01-01

Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays.

by Ridha Limame, An Wouters, Bea Pauwels, Erik Fransen, Marc Peeters, Filip Lardon, Olivier De Wever, Patrick Pauwels
Published 2012-01-01

Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib

by Ines De Pauw, Filip Lardon, Jolien Van den Bossche, Hasan Baysal, Patrick Pauwels, Marc Peeters, Jan Baptist Vermorken, An Wouters
Published 2019-01-01

Targeting the PD-1 Axis with Pembrolizumab for Recurrent or Metastatic Cancer of the Uterine Cervix: A Brief Update

by Yannick Verhoeven, Delphine Quatannens, Xuan Bich Trinh, An Wouters, Evelien L.J. Smits, Filip Lardon, Jorrit De Waele, Peter A. van Dam
Published 2021-02-01

A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy

by Jorrit De Waele, Tias Verhezen, Sanne van der Heijden, Zwi N. Berneman, Marc Peeters, Filip Lardon, An Wouters, Evelien L. J. M. Smits
Published 2021-06-01

Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines

by Ines De Pauw, Filip Lardon, Jolien Van den Bossche, Hasan Baysal, Erik Fransen, Vanessa Deschoolmeester, Patrick Pauwels, Marc Peeters, Jan Baptist Vermorken, An Wouters
Published 2018-06-01

The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma

by Mohammad Krayem, Malak Sabbah, Ahmad Najem, An Wouters, Filip Lardon, Stephane Simon, François Sales, Fabrice Journe, Ahmad Awada, Ghanem E. Ghanem, Dirk Van Gestel
Published 2019-08-01

The Right Partner in Crime: Unlocking the Potential of the Anti-EGFR Antibody Cetuximab via Combination With Natural Killer Cell Chartering Immunotherapeutic Strategies

by Hasan Baysal, Ines De Pauw, Hannah Zaryouh, Marc Peeters, Marc Peeters, Jan Baptist Vermorken, Jan Baptist Vermorken, Filip Lardon, Jorrit De Waele, An Wouters
Published 2021-09-01

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

by Christophe Deben, Vanessa Deschoolmeester, Jorrit De Waele, Julie Jacobs, Jolien Van den Bossche, An Wouters, Marc Peeters, Christian Rolfo, Evelien Smits, Filip Lardon, Patrick Pauwels
Published 2018-04-01

The Role of Akt in Acquired Cetuximab Resistant Head and Neck Squamous Cell Carcinoma: An In Vitro Study on a Novel Combination Strategy

by Hannah Zaryouh, Ines De Pauw, Hasan Baysal, Patrick Pauwels, Patrick Pauwels, Marc Peeters, Marc Peeters, Jan Baptist Vermorken, Jan Baptist Vermorken, Filip Lardon, An Wouters
Published 2021-09-01

Clinically Relevant Chemotherapeutics Have the Ability to Induce Immunogenic Cell Death in Non-Small Cell Lung Cancer

by Tal Flieswasser, Jinthe Van Loenhout, Laurie Freire Boullosa, Astrid Van den Eynde, Jorrit De Waele, Jonas Van Audenaerde, Filip Lardon, Evelien Smits, Patrick Pauwels, Julie Jacobs
Published 2020-06-01

In vitro study of the Polo‐like kinase 1 inhibitor volasertib in non‐small‐cell lung cancer reveals a role for the tumor suppressor p53

by Jolien Van denBossche, Christophe Deben, Ines De Pauw, Hilde Lambrechts, Christophe Hermans, Vanessa Deschoolmeester, Julie Jacobs, Pol Specenier, Patrick Pauwels, Jan Baptist Vermorken, Marc Peeters, Filip Lardon, An Wouters
Published 2019-05-01

Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer

by Andreas Domen, Delphine Quatannens, Sara Zanivan, Christophe Deben, Jonas Van Audenaerde, Evelien Smits, An Wouters, Filip Lardon, Geert Roeyen, Yannick Verhoeven, Annelies Janssens, Timon Vandamme, Peter van Dam, Marc Peeters, Hans Prenen
Published 2021-02-01

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

by Julie Jacobs, Vanessa Deschoolmeester, Karen Zwaenepoel, Tal Flieswasser, Christophe Deben, Jolien Van den Bossche, Christophe Hermans, Christian Rolfo, Marc Peeters, Olivier De Wever, Filip Lardon, Vasiliki Siozopoulou, Evelien Smits, Patrick Pauwels
Published 2018-07-01

Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol

by Laure Sorber, Karen Zwaenepoel, Julie Jacobs, Koen De Winne, Sofie Goethals, Pablo Reclusa, Kaat Van Casteren, Elien Augustus, Filip Lardon, Geert Roeyen, Marc Peeters, Jan Van Meerbeeck, Christian Rolfo, Patrick Pauwels
Published 2019-03-01

453 Novel combination immunotherapy for boosting and priming immune responses in pancreatic cancer: strong anti-tumour effects with interleukin-15 and CD40 agonist treatment

by Patrick Pauwels, Marc Peeters, Jonas Van Audenaerde, Elly Marcq, Bianca von Scheidt, Ashleigh Davey, Amanda Oliver, Jorrit De Waele, Delphine Quatannens, Jinthe Van Loenhout, Geert Roeyen, Filip Lardon, Clare Slaney, Evelien Smits
Published 2020-11-01

RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review

by Peter A. van Dam, Yannick Verhoeven, Julie Jacobs, An Wouters, Wiebren Tjalma, Filip Lardon, Tim Van den Wyngaert, Jonatan Dewulf, Evelien Smits, Cécile Colpaert, Hans Prenen, Marc Peeters, Martin Lammens, Xuan Bich Trinh
Published 2019-05-01

Deep sequencing of the gene reveals a potential risk allele for non–small cell lung cancer and supports the negative prognostic value of variants

by Christophe Deben, Jolien Van den Bossche, Nele Van Der Steen, Filip Lardon, An Wouters, Ken Op de Beeck, Christophe Hermans, Julie Jacobs, Marc Peeters, Guy Van Camp, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels
Published 2017-02-01

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.

by Katarzyna Szarc vel Szic, Ken Op de Beeck, Dariusz Ratman, An Wouters, Ilse M Beck, Ken Declerck, Karen Heyninck, Erik Fransen, Marc Bracke, Karolien De Bosscher, Filip Lardon, Guy Van Camp, Wim Vanden Berghe
Published 2014-01-01