Oxidative Stress-Inducing Anticancer Therapies: Taking a Closer Look at Their Immunomodulating Effects

by Jinthe Van Loenhout, Marc Peeters, Annemie Bogaerts, Evelien Smits, Christophe Deben
Published 2020-11-01

Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients

by Eline Berghmans, Julie Jacobs, Christophe Deben, Christophe Hermans, Glenn Broeckx, Evelien Smits, Evelyne Maes, Jo Raskin, Patrick Pauwels, Geert Baggerman
Published 2020-04-01

The Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment

by Eline Biscop, Abraham Lin, Wilma Van Boxem, Jinthe Van Loenhout, Joey De Backer, Christophe Deben, Sylvia Dewilde, Evelien Smits, Annemie Bogaerts
Published 2019-09-01

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

by Christophe Deben, Vanessa Deschoolmeester, Jorrit De Waele, Julie Jacobs, Jolien Van den Bossche, An Wouters, Marc Peeters, Christian Rolfo, Evelien Smits, Filip Lardon, Patrick Pauwels
Published 2018-04-01

In vitro study of the Polo‐like kinase 1 inhibitor volasertib in non‐small‐cell lung cancer reveals a role for the tumor suppressor p53

by Jolien Van denBossche, Christophe Deben, Ines De Pauw, Hilde Lambrechts, Christophe Hermans, Vanessa Deschoolmeester, Julie Jacobs, Pol Specenier, Patrick Pauwels, Jan Baptist Vermorken, Marc Peeters, Filip Lardon, An Wouters
Published 2019-05-01

Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer

by Andreas Domen, Delphine Quatannens, Sara Zanivan, Christophe Deben, Jonas Van Audenaerde, Evelien Smits, An Wouters, Filip Lardon, Geert Roeyen, Yannick Verhoeven, Annelies Janssens, Timon Vandamme, Peter van Dam, Marc Peeters, Hans Prenen
Published 2021-02-01

Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation

by Julie Jacobs, Vanessa Deschoolmeester, Karen Zwaenepoel, Tal Flieswasser, Christophe Deben, Jolien Van den Bossche, Christophe Hermans, Christian Rolfo, Marc Peeters, Olivier De Wever, Filip Lardon, Vasiliki Siozopoulou, Evelien Smits, Patrick Pauwels
Published 2018-07-01

Deep sequencing of the gene reveals a potential risk allele for non–small cell lung cancer and supports the negative prognostic value of variants

by Christophe Deben, Jolien Van den Bossche, Nele Van Der Steen, Filip Lardon, An Wouters, Ken Op de Beeck, Christophe Hermans, Julie Jacobs, Marc Peeters, Guy Van Camp, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels
Published 2017-02-01

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer

by Laurie Freire Boullosa, Jinthe Van Loenhout, Tal Flieswasser, Jorrit De Waele, Christophe Hermans, Hilde Lambrechts, Bart Cuypers, Kris Laukens, Esther Bartholomeus, Vasiliki Siozopoulou, Winnok H. De Vos, Marc Peeters, Evelien L.J. Smits, Christophe Deben
Published 2021-06-01

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

by Jinthe Van Loenhout, Tal Flieswasser, Laurie Freire Boullosa, Jorrit De Waele, Jonas Van Audenaerde, Elly Marcq, Julie Jacobs, Abraham Lin, Eva Lion, Heleen Dewitte, Marc Peeters, Sylvia Dewilde, Filip Lardon, Annemie Bogaerts, Christophe Deben, Evelien Smits
Published 2019-10-01

Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade

by Jorrit De Waele, Elly Marcq, Jonas RM Van Audenaerde, Jinthe Van Loenhout, Christophe Deben, Karen Zwaenepoel, Erik Van de Kelft, David Van der Planken, Tomas Menovsky, Johan MJ Van den Bergh, Yannick Willemen, Patrick Pauwels, Zwi N Berneman, Filip Lardon, Marc Peeters, An Wouters, Evelien LJ Smits
Published 2018-03-01