mRNA in cancer immunotherapy: beyond a source of antigen

by Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Ine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
Published 2021-03-01

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon

by Katrijn Broos, Kevin Van der Jeught, Janik Puttemans, Cleo Goyvaerts, Carlo Heirman, Heleen Dewitte, Rein Verbeke, Ine Lentacker, Kris Thielemans, Karine Breckpot
Published 2016-01-01

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice

by Lien Van Hoecke, Rein Verbeke, Dorien De Vlieger, Heleen Dewitte, Kenny Roose, Sharon Van Nevel, Olga Krysko, Claus Bachert, Bert Schepens, Ine Lentacker, Xavier Saelens
Published 2020-06-01

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells

by Jinthe Van Loenhout, Tal Flieswasser, Laurie Freire Boullosa, Jorrit De Waele, Jonas Van Audenaerde, Elly Marcq, Julie Jacobs, Abraham Lin, Eva Lion, Heleen Dewitte, Marc Peeters, Sylvia Dewilde, Filip Lardon, Annemie Bogaerts, Christophe Deben, Evelien Smits
Published 2019-10-01