mRNA in cancer immunotherapy: beyond a source of antigen

by Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Ine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
Published 2021-03-01

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon

by Katrijn Broos, Kevin Van der Jeught, Janik Puttemans, Cleo Goyvaerts, Carlo Heirman, Heleen Dewitte, Rein Verbeke, Ine Lentacker, Kris Thielemans, Karine Breckpot
Published 2016-01-01

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice

by Lien Van Hoecke, Rein Verbeke, Dorien De Vlieger, Heleen Dewitte, Kenny Roose, Sharon Van Nevel, Olga Krysko, Claus Bachert, Bert Schepens, Ine Lentacker, Xavier Saelens
Published 2020-06-01

Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation

by Laurens Raes, Stephan Stremersch, Juan C. Fraire, Toon Brans, Glenn Goetgeluk, Stijn De Munter, Lien Van Hoecke, Rein Verbeke, Jelter Van Hoeck, Ranhua Xiong, Xavier Saelens, Bart Vandekerckhove, Stefaan De Smedt, Koen Raemdonck, Kevin Braeckmans
Published 2020-09-01

Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis

by Shweta Saini, Jennifer Poelmans, Hannelie Korf, James L. Dooley, Sayuan Liang, Bella B. Manshian, Rein Verbeke, Stefaan J. Soenen, Greetje Vande Velde, Ine Lentacker, Katrien Lagrou, Adrian Liston, Conny Gysemans, Stefaan C. De Smedt, Uwe Himmelreich
Published 2019-10-01