How mRNA therapeutics are entering the monoclonal antibody field

by Lien Van Hoecke, Kenny Roose
Published 2019-02-01

Influenza and Memory T Cells: How to Awake the Force

by Jan Spitaels, Kenny Roose, Xavier Saelens
Published 2016-10-01

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.

by Jonathan Maelfait, Kenny Roose, Pieter Bogaert, Mozes Sze, Xavier Saelens, Manolis Pasparakis, Isabelle Carpentier, Geert van Loo, Rudi Beyaert
Published 2012-01-01

Correction: A20 () Deficiency in Myeloid Cells Protects against Influenza A Virus Infection.

by Jonathan Maelfait, Kenny Roose, Pieter Bogaert, Mozes Sze, Xavier Saelens, Manolis Pasparakis, Isabelle Carpentier, Geert van Loo, Rudi Beyaert
Published 2012-04-01

The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration

by Lien Van Hoecke, Kenny Roose, Marlies Ballegeer, Zifu Zhong, Niek N. Sanders, Stefaan De Koker, Xavier Saelens, Sandra Van Lint
Published 2020-12-01

Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages.

by Lei Deng, Lorena Itatí Ibañez, Veronique Van den Bossche, Kenny Roose, Sameh A Youssef, Alain de Bruin, Walter Fiers, Xavier Saelens
Published 2015-01-01

Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes

by Lien Van Hoecke, Sandra Van Lint, Kenny Roose, Alexander Van Parys, Peter Vandenabeele, Johan Grooten, Jan Tavernier, Stefaan De Koker, Xavier Saelens
Published 2018-08-01

A GFP expressing influenza A virus to report in vivo tropism and protection by a matrix protein 2 ectodomain-specific monoclonal antibody.

by Sarah De Baets, Judith Verhelst, Silvie Van den Hoecke, Anouk Smet, Michael Schotsaert, Emma R Job, Kenny Roose, Bert Schepens, Walter Fiers, Xavier Saelens
Published 2015-01-01

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice

by Lien Van Hoecke, Rein Verbeke, Dorien De Vlieger, Heleen Dewitte, Kenny Roose, Sharon Van Nevel, Olga Krysko, Claus Bachert, Bert Schepens, Ine Lentacker, Xavier Saelens
Published 2020-06-01

M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

by Lorena Itatí Ibañez, Kenny Roose, Marina De Filette, Michael Schotsaert, Jessica De Sloovere, Stefan Roels, Charlotte Pollard, Bert Schepens, Johan Grooten, Walter Fiers, Xavier Saelens
Published 2013-01-01

Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization

by Annelies Leemans, Marlies Boeren, Winke Van der Gucht, Isabel Pintelon, Kenny Roose, Bert Schepens, Xavier Saelens, Dalan Bailey, Wim Martinet, Guy Caljon, Louis Maes, Paul Cos, Peter Delputte
Published 2018-08-01

A20 Deficiency in Lung Epithelial Cells Protects against Influenza A Virus Infection.

by Jonathan Maelfait, Kenny Roose, Lars Vereecke, Conor Mc Guire, Mozes Sze, Martijn J Schuijs, Monique Willart, Lorena Itati Ibañez, Hamida Hammad, Bart N Lambrecht, Rudi Beyaert, Xavier Saelens, Geert van Loo
Published 2016-01-01

Reverse engineering synthetic antiviral amyloids

by Emiel Michiels, Kenny Roose, Rodrigo Gallardo, Ladan Khodaparast, Laleh Khodaparast, Rob van der Kant, Maxime Siemons, Bert Houben, Meine Ramakers, Hannah Wilkinson, Patricia Guerreiro, Nikolaos Louros, Suzanne J. F. Kaptein, Lorena Itatí Ibañez, Anouk Smet, Pieter Baatsen, Shu Liu, Ina Vorberg, Guy Bormans, Johan Neyts, Xavier Saelens, Frederic Rousseau, Joost Schymkowitz
Published 2020-06-01

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

by Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein, Rong Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Carolien De Keyzer, Lindsey Bervoets, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, Dominique Van Looveren, Thomas Vercruysse, Xinyu Wang, Dirk Jochmans, Erik Martens, Kenny Roose, Dorien De Vlieger, Bert Schepens, Tina Van Buyten, Sofie Jacobs, Yanan Liu, Joan Martí-Carreras, Bert Vanmechelen, Tony Wawina-Bokalanga, Leen Delang, Joana Rocha-Pereira, Lotte Coelmont, Winston Chiu, Pieter Leyssen, Elisabeth Heylen, Dominique Schols, Lanjiao Wang, Lila Close, Jelle Matthijnssens, Marc Van Ranst, Veerle Compernolle, Georg Schramm, Koen Van Laere, Xavier Saelens, Nico Callewaert, Ghislain Opdenakker, Piet Maes, Birgit Weynand, Christopher Cawthorne, Greetje Vande Velde, Zhongde Wang, Johan Neyts, Kai Dallmeier
Published 2020-11-01