IgG3 Snitcher of RSV Infections in the Very Young

by Bert Schepens, Xavier Saelens
Published 2017-02-01

Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses.

by Koen Sedeyn, Bert Schepens, Xavier Saelens
Published 2019-10-01

Single-Domain Antibodies and Their Formatting to Combat Viral Infections

by Dorien De Vlieger, Marlies Ballegeer, Iebe Rossey, Bert Schepens, Xavier Saelens
Published 2018-12-01

Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

by Patrick Tjok Joe, Ioanna Christopoulou, Lien van Hoecke, Bert Schepens, Tine Ysenbaert, Carlo Heirman, Kris Thielemans, Xavier Saelens, Joeri L. Aerts
Published 2019-07-01

A GFP expressing influenza A virus to report in vivo tropism and protection by a matrix protein 2 ectodomain-specific monoclonal antibody.

by Sarah De Baets, Judith Verhelst, Silvie Van den Hoecke, Anouk Smet, Michael Schotsaert, Emma R Job, Kenny Roose, Bert Schepens, Walter Fiers, Xavier Saelens
Published 2015-01-01

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice

by Lien Van Hoecke, Rein Verbeke, Dorien De Vlieger, Heleen Dewitte, Kenny Roose, Sharon Van Nevel, Olga Krysko, Claus Bachert, Bert Schepens, Ine Lentacker, Xavier Saelens
Published 2020-06-01

M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

by Lorena Itatí Ibañez, Kenny Roose, Marina De Filette, Michael Schotsaert, Jessica De Sloovere, Stefan Roels, Charlotte Pollard, Bert Schepens, Johan Grooten, Walter Fiers, Xavier Saelens
Published 2013-01-01

Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection

by Dorien De Vlieger, Dorien De Vlieger, Dorien De Vlieger, Katja Hoffmann, Inge Van Molle, Inge Van Molle, Wim Nerinckx, Wim Nerinckx, Lien Van Hoecke, Lien Van Hoecke, Marlies Ballegeer, Marlies Ballegeer, Marlies Ballegeer, Sarah Creytens, Sarah Creytens, Sarah Creytens, Han Remaut, Han Remaut, Hartmut Hengel, Bert Schepens, Bert Schepens, Xavier Saelens, Xavier Saelens, Xavier Saelens
Published 2019-12-01

Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization

by Annelies Leemans, Marlies Boeren, Winke Van der Gucht, Isabel Pintelon, Kenny Roose, Bert Schepens, Xavier Saelens, Dalan Bailey, Wim Martinet, Guy Caljon, Louis Maes, Paul Cos, Peter Delputte
Published 2018-08-01

Correction: Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

by Iebe Rossey, Morgan S. A. Gilman, Stephanie C. Kabeche, Koen Sedeyn, Daniel Wrapp, Masaru Kanekiyo, Man Chen, Vicente Mas, Jan Spitaels, José A. Melero, Barney S. Graham, Bert Schepens, Jason S. McLellan, Xavier Saelens
Published 2017-11-01

Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

by Iebe Rossey, Morgan S. A. Gilman, Stephanie C. Kabeche, Koen Sedeyn, Daniel Wrapp, Masaru Kanekiyo, Man Chen, Vicente Mas, Jan Spitaels, José A. Melero, Barney S. Graham, Bert Schepens, Jason S. McLellan, Xavier Saelens
Published 2017-02-01

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules.

by Anna Hultberg, Nigel J Temperton, Valérie Rosseels, Mireille Koenders, Maria Gonzalez-Pajuelo, Bert Schepens, Lorena Itatí Ibañez, Peter Vanlandschoot, Joris Schillemans, Michael Saunders, Robin A Weiss, Xavier Saelens, José A Melero, C Theo Verrips, Steven Van Gucht, Hans J de Haard
Published 2011-04-01

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

by Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne J. F. Kaptein, Rong Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Carolien De Keyzer, Lindsey Bervoets, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, Dominique Van Looveren, Thomas Vercruysse, Xinyu Wang, Dirk Jochmans, Erik Martens, Kenny Roose, Dorien De Vlieger, Bert Schepens, Tina Van Buyten, Sofie Jacobs, Yanan Liu, Joan Martí-Carreras, Bert Vanmechelen, Tony Wawina-Bokalanga, Leen Delang, Joana Rocha-Pereira, Lotte Coelmont, Winston Chiu, Pieter Leyssen, Elisabeth Heylen, Dominique Schols, Lanjiao Wang, Lila Close, Jelle Matthijnssens, Marc Van Ranst, Veerle Compernolle, Georg Schramm, Koen Van Laere, Xavier Saelens, Nico Callewaert, Ghislain Opdenakker, Piet Maes, Birgit Weynand, Christopher Cawthorne, Greetje Vande Velde, Zhongde Wang, Johan Neyts, Kai Dallmeier
Published 2020-11-01