Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs.

by Xuezhi Zhang, Karl-Heinz Krause, Ioannis Xenarios, Thierry Soldati, Brigitte Boeckmann
Published 2013-01-01

Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation

by Olivier Preynat-Seauve, Olivier Preynat-Seauve, Evelyne Bao-Vi Nguyen, Yvonne Westermaier, Margaux Héritier, Sébastien Tardy, Yves Cambet, Maxime Feyeux, Aurélie Caillon, Leonardo Scapozza, Karl-Heinz Krause, Karl-Heinz Krause
Published 2021-08-01

Modeling Poliovirus Infection Using Human Engineered Neural Tissue Enriched With Motor Neuron Derived From Embryonic Stem Cells

by Érika Cosset, Youssef Hibaoui, Sten Ilmjärv, Pierre-Yves Dietrich, Caroline Tapparel, Karl-Heinz Krause
Published 2021-01-01

Generation of human induced pluripotent stem cell line UNIGEi003-A from skin fibroblasts of an apparently healthy male donor

by Erika Cosset, Tieng Vannary, Frédérique Sloan-Béna, Stefania Gimelli, Eric Gerstel, Karl-Heinz Krause, Antoine Marteyn
Published 2020-10-01

Optimization of Critical Hairpin Features Allows miRNA-based Gene Knockdown Upon Single-copy Transduction

by Renier Myburgh, Ophélie Cherpin, Erika Schlaepfer, Hubert Rehrauer, Roberto F Speck, Karl-Heinz Krause, Patrick Salmon
Published 2014-01-01

Fate of systemically and locally administered adipose‐derived mesenchymal stromal cells and their effect on wound healing

by Karlien Kallmeyer, Dominik André‐Lévigne, Mathurin Baquié, Karl‐Heinz Krause, Michael S. Pepper, Brigitte Pittet‐Cuénod, Ali Modarressi
Published 2020-01-01

Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampus

by Natalia Robledinos-Antón, Ana I. Rojo, Elisabete Ferreiro, Ángel Núñez, Karl-Heinz Krause, Vincent Jaquet, Antonio Cuadrado
Published 2017-10-01

Hydrogen Peroxide Affects Growth of S. aureus Through Downregulation of Genes Involved in Pyrimidine Biosynthesis

by Hélène Buvelot, Myriam Roth, Vincent Jaquet, Andrey Lozkhin, Adriana Renzoni, Eve-Julie Bonetti, Nadia Gaia, Floriane Laumay, Michéle Mollin, Marie-José. Stasia, Marie-José. Stasia, Jacques Schrenzel, Jacques Schrenzel, Patrice François, Karl-Heinz Krause, Karl-Heinz Krause
Published 2021-09-01

Induced Pluripotent Stem Cells to Understand Mucopolysaccharidosis. I: Demonstration of a Migration Defect in Neural Precursors

by Silvin Lito, Adama Sidibe, Sten Ilmjarv, Patricie Burda, Matthias Baumgartner, Bernhard Wehrle-Haller, Karl-Heinz Krause, Antoine Marteyn
Published 2020-12-01

Elimination of proliferating cells from CNS grafts using a Ki67 promoter-driven thymidine kinase

by Vannary Tieng, Ophelie Cherpin, Eveline Gutzwiller, Alexander C Zambon, Christophe Delgado, Patrick Salmon, Michel Dubois-Dauphin, Karl-Heinz Krause
Published 2016-01-01

Generation of human induced pluripotent stem cell line UNIGEi001-A from a 2-years old patient with Mucopolysaccharidosis type IH disease

by Silvin Lito, Patricie Burda, Matthias Baumgartner, Frédérique Sloan-Béna, Zsuzsanna Táncos, Julianna Kobolák, András Dinnyés, Karl-Heinz Krause, Antoine Marteyn
Published 2019-12-01

Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant

by Sten Ilmjärv, Fabien Abdul, Silvia Acosta-Gutiérrez, Carolina Estarellas, Ioannis Galdadas, Marina Casimir, Marco Alessandrini, Francesco Luigi Gervasio, Karl-Heinz Krause
Published 2021-07-01

Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects

by German Nacher-Soler, Sébastien Lenglet, Marta Coelho, Aurélien Thomas, Aurélien Thomas, François Voruz, François Voruz, Karl-Heinz Krause, Pascal Senn, Pascal Senn, Francis Rousset
Published 2021-07-01

Altered Humoral Immune Responses and IgG Subtypes in NOX2-Deficient Mice and Patients: A Key Role for NOX2 in Antigen-Presenting Cells

by Julien Cachat, Christine Deffert, Marco Alessandrini, Pascale Roux-Lombard, Audrey Le Gouellec, Audrey Le Gouellec, Marie-José Stasia, Marie-José Stasia, Stéphanie Hugues, Karl-Heinz Krause
Published 2018-07-01

Viral chimeras decrypt the role of enterovirus capsid proteins in viral tropism, acid sensitivity and optimal growth temperature.

by Léna Royston, Manel Essaidi-Laziosi, Francisco J Pérez-Rodríguez, Isabelle Piuz, Johan Geiser, Karl-Heinz Krause, Song Huang, Samuel Constant, Laurent Kaiser, Dominique Garcin, Caroline Tapparel
Published 2018-04-01

Optimizing Synthetic miRNA Minigene Architecture for Efficient miRNA Hairpin Concatenation and Multi-target Gene Knockdown

by Francis Rousset, Patrick Salmon, Simon Bredl, Ophélie Cherpin, Marta Coelho, Renier Myburgh, Marco Alessandrini, Michael Perny, Marta Roccio, Roberto F. Speck, Pascal Senn, Karl Heinz Krause
Published 2019-03-01

Redox activation of excitatory pathways in auditory neurons as mechanism of age-related hearing loss

by Francis Rousset, German Nacher-Soler, Marta Coelho, Sten Ilmjarv, Vivianne Beatrix Christina Kokje, Antoine Marteyn, Yves Cambet, Michael Perny, Marta Roccio, Vincent Jaquet, Pascal Senn, Karl Heinz Krause
Published 2020-02-01

Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation.

by Christine Deffert, Michela G Schäppi, Jean-Claude Pache, Julien Cachat, Dominique Vesin, Ruth Bisig, Xiaojuan Ma Mulone, Tiina Kelkka, Rikard Holmdahl, Irene Garcia, Maria L Olleros, Karl-Heinz Krause
Published 2014-09-01

Pharmacological characterization of the seven human NOX isoforms and their inhibitors

by Fiona Augsburger, Aleksandra Filippova, Delphine Rasti, Tamara Seredenina, Magdalena Lam, Ghassan Maghzal, Zahia Mahiout, Pidder Jansen-Dürr, Ulla G. Knaus, James Doroshow, Roland Stocker, Karl-Heinz Krause, Vincent Jaquet
Published 2019-09-01

Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC

by Zeynab Nayernia, Marilena Colaianna, Natalia Robledinos-Antón, Eveline Gutzwiller, Frédérique Sloan-Béna, Elisavet Stathaki, Yousef Hibaoui, Antonio Cuadrado, Jürgen Hescheler, Marie-José Stasia, Tomo Saric, Vincent Jaquet, Karl-Heinz Krause
Published 2017-10-01