The two faces of Janus kinases and their respective STATs in mammary gland development and cancer

by Kay-Uwe Wagner, Jeffrey W Schmidt
Published 2011-01-01

Generation of a novel MMTV-tTA transgenic mouse strain for the targeted expression of genes in the embryonic and postnatal mammary gland.

by Kazuhito Sakamoto, Jeffrey W Schmidt, Kay-Uwe Wagner
Published 2012-01-01

A Mammary-Specific, Long-range Deletion on Mouse Chromosome 11 Accelerates Brca1-Associated Mammary Tumorigenesis

by Aleata A. Triplett, Cristina Montagna, Kay-Uwe Wagner
Published 2008-12-01

Tumor susceptibility gene 101 is required for the maintenance of uterine epithelial cells during embryo implantation

by Hyunji Byun, Sojung Kwon, Kay-Uwe Wagner, Hyejin Shin, Hyunjung Jade Lim
Published 2021-07-01

Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers

by Nirakar Rajbhandari, Wan-chi Lin, Barbara L. Wehde, Aleata A. Triplett, Kay-Uwe Wagner
Published 2017-02-01

The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease

by Rosa-Maria Ferraiuolo, Karoline C. Manthey, Marissa J. Stanton, Aleata A. Triplett, Kay-Uwe Wagner
Published 2020-02-01

Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.

by Wan-chi Lin, Jeffrey W Schmidt, Bradley A Creamer, Aleata A Triplett, Kay-uwe Wagner
Published 2013-01-01

A knockout of the Tsg101 gene leads to decreased expression of ErbB receptor tyrosine kinases and induction of autophagy prior to cell death.

by Chantey R Morris, Marissa J Stanton, Karoline C Manthey, Keon Bong Oh, Kay-Uwe Wagner
Published 2012-01-01

IRF4 is a suppressor of c-Myc induced B cell leukemia.

by Simanta Pathak, Shibin Ma, Long Trinh, James Eudy, Kay-Uwe Wagner, Shantaram S Joshi, Runqing Lu
Published 2011-01-01

Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression

by Barbara L. Wehde, Patrick D. Rädler, Hridaya Shrestha, Stevi J. Johnson, Aleata A. Triplett, Kay-Uwe Wagner
Published 2018-11-01

Exosomal microRNA in Pancreatic Cancer Diagnosis, Prognosis, and Treatment: From Bench to Bedside

by Md. Hafiz Uddin, Mohammed Najeeb Al-Hallak, Philip A. Philip, Ramzi M. Mohammad, Nerissa Viola, Kay-Uwe Wagner, Asfar S. Azmi
Published 2021-06-01

Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans.

by Sung O Park, Heather L Wamsley, Kyungmi Bae, Zhongbo Hu, Xiaomiao Li, Se-woon Choe, William B Slayton, S Paul Oh, Kay-Uwe Wagner, Peter P Sayeski
Published 2013-01-01

Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells

by Patrick D. Rädler, Barbara L. Wehde, Aleata A. Triplett, Hridaya Shrestha, Jonathan H. Shepherd, Adam D. Pfefferle, Hallgeir Rui, Robert D. Cardiff, Charles M. Perou, Kay-Uwe Wagner
Published 2021-06-01

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

by Harsh R. Desai, Tharini Sivasubramaniyam, Xavier S. Revelo, Stephanie A. Schroer, Cynthia T. Luk, Prashanth R. Rikkala, Adam H. Metherel, David W. Dodington, Yoo Jin Park, Min Jeong Kim, Joshua A. Rapps, Rickvinder Besla, Clinton S. Robbins, Kay-Uwe Wagner, Richard P. Bazinet, Daniel A. Winer, Minna Woo
Published 2017-08-01