High-content siRNA 3D co-cultures to identify myoepithelial cell-derived breast cancer suppressor proteins

by Hendrika M. Duivenvoorden, Natasha K. Brockwell, Cameron J. Nowell, Kaylene J. Simpson, Belinda S. Parker
Published 2021-05-01

Signalome-wide assessment of host cell response to hepatitis C virus

by Gholamreza Haqshenas, Jianmin Wu, Kaylene J. Simpson, Roger J. Daly, Hans J. Netter, Thomas F. Baumert, Christian Doerig
Published 2017-05-01

Loss of HPV type 16 E7 restores cGAS-STING responses in human papilloma virus-positive oropharyngeal squamous cell carcinomas cells

by Vuk Bortnik, Michelle Wu, Bryan Julcher, Ana Salinas, Iva Nikolic, Kaylene J. Simpson, Nigel AJ. McMillan, Adi Idris
Published 2021-08-01

Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen.

by Lauren E King, Hui-Hua Zhang, Cathryn M Gould, Daniel W Thomas, Lachlan W Whitehead, Kaylene J Simpson, Antony W Burgess, Maree C Faux
Published 2020-01-01

FGFR3 signaling and function in triple negative breast cancer

by Nicole J. Chew, Elizabeth V. Nguyen, Shih-Ping Su, Karel Novy, Howard C. Chan, Lan K. Nguyen, Jennii Luu, Kaylene J. Simpson, Rachel S. Lee, Roger J. Daly
Published 2020-01-01

Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens.

by Žaklina Strezoska, Abel Licon, Josh Haimes, Katie Jansen Spayd, Kruti M Patel, Kevin Sullivan, Katarzyna Jastrzebski, Kaylene J Simpson, Devin Leake, Anja van Brabant Smith, Annaleen Vermeulen
Published 2012-01-01

Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen

by Sugandha Bhatia, Tony Blick, Cletus Pinto, Mark Waltham, James Monkman, Ekaterina Ivanova, Pamela M. Pollock, Shivashankar H. Nagaraj, Adrian P. Wiegmans, Izhak Haviv, Kaylene J. Simpson, Erik W. Thompson
Published 2020-04-01

An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

by Bhaskar Dutta, Alaleh Azhir, Louis-Henri Merino, Yongjian Guo, Swetha Revanur, Piyush B. Madhamshettiwar, Ronald N. Germain, Jennifer A. Smith, Kaylene J. Simpson, Scott E. Martin, Eugen Buehler, Iain D. C. Fraser
Published 2016-02-01

Correction: Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

by Bhaskar Dutta, Alaleh Azhir, Louis-Henri Merino, Yongjian Guo, Swetha Revanur, Piyush B. Madhamshettiwar, Ronald N. Germain, Jennifer A. Smith, Kaylene J. Simpson, Scott E. Martin, Eugen Buehler, Iain D. C. Fraser
Published 2016-03-01

Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus

by Yaqing Jiao, Sarah Preston, Anson V. Koehler, Andreas J. Stroehlein, Bill C. H. Chang, Kaylene J. Simpson, Karla J. Cowley, Michael J. Palmer, Benoît Laleu, Timothy N. C. Wells, Abdul Jabbar, Robin B. Gasser
Published 2017-07-01

Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the ba...

by Sarah Preston, Yaqing Jiao, Jonathan B. Baell, Jennifer Keiser, Simon Crawford, Anson V. Koehler, Tao Wang, Moana M. Simpson, Ray M. Kaplan, Karla J. Cowley, Kaylene J. Simpson, Andreas Hofmann, Abdul Jabbar, Robin B. Gasser
Published 2017-12-01

Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation

by Xiuquan Ma, Luxi Zhang, Jiangning Song, Elizabeth Nguyen, Rachel S. Lee, Samuel J. Rodgers, Fuyi Li, Cheng Huang, Ralf B. Schittenhelm, Howard Chan, Chanly Chheang, Jianmin Wu, Kristin K. Brown, Christina A. Mitchell, Kaylene J. Simpson, Roger J. Daly
Published 2019-01-01

Dual microRNA Screens Reveal That the Immune-Responsive miR-181 Promotes Henipavirus Entry and Cell-Cell Fusion.

by Chwan Hong Foo, Christina L Rootes, Karla Cowley, Glenn A Marsh, Cathryn M Gould, Celine Deffrasnes, Christopher J Cowled, Reuben Klein, Sarah J Riddell, Deborah Middleton, Kaylene J Simpson, Lin-Fa Wang, Andrew G D Bean, Cameron R Stewart
Published 2016-10-01

A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death

by Sophia Ceder, Sofi E Eriksson, Emarndeena H Cheteh, Swati Dawar, Mariana Corrales Benitez, Vladimir J N Bykov, Kenji M Fujihara, Mélodie Grandin, Xiaodun Li, Susanne Ramm, Corina Behrenbruch, Kaylene J Simpson, Frédéric Hollande, Lars Abrahmsen, Nicholas J Clemons, Klas G Wiman
Published 2021-02-01

Metabolic profiling and in vitro assessment of anthelmintic fractions of Picria fel-terrae Lour.

by Rasika Kumarasingha, Avinash V. Karpe, Sarah Preston, Tiong-Chia Yeo, Diana S.L. Lim, Chu-Lee Tu, Jennii Luu, Kaylene J. Simpson, Jillian M. Shaw, Robin B. Gasser, David J. Beale, Paul D. Morrison, Enzo A. Palombo, Peter R. Boag
Published 2016-12-01

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection.

by Celine Deffrasnes, Glenn A Marsh, Chwan Hong Foo, Christina L Rootes, Cathryn M Gould, Julian Grusovin, Paul Monaghan, Michael K Lo, S Mark Tompkins, Timothy E Adams, John W Lowenthal, Kaylene J Simpson, Cameron R Stewart, Andrew G D Bean, Lin-Fa Wang
Published 2016-03-01

A genome-wide Drosophila epithelial tumorigenesis screen identifies Tetraspanin 29Fb as an evolutionarily conserved suppressor of Ras-driven cancer.

by Tamara Zoranovic, Jan Manent, Lee Willoughby, Ricardo Matos de Simoes, John E La Marca, Sofya Golenkina, Xia Cuiping, Susanne Gruber, Belinda Angjeli, Elisabeth Eva Kanitz, Shane J F Cronin, G Gregory Neely, G Gregory Neely, Andreas Wernitznig, Patrick O Humbert, Kaylene J Simpson, Constantine S Mitsiades, Helena E Richardson, Josef M Penninger
Published 2018-10-01