Epigenetics and Colorectal Cancer Pathogenesis

by Kebin Liu, Kankana Bardhan
Published 2013-06-01

Epigenetic regulation of apoptosis and cell cycle regulatory genes in human colon carcinoma cells

by Amy V. Paschall, Kebin Liu
Published 2015-09-01

JAK-STAT-mediated chronic inflammation impairs cytotoxic T lymphocyte activation to decrease anti-PD-1 immunotherapy efficacy in pancreatic cancer

by Chunwan Lu, Asif Talukder, Natasha M. Savage, Nagendra Singh, Kebin Liu
Published 2017-03-01

A Multi-Frequency Patch Antenna With Double Sided Parallel Strip Line Periodic Structure

by Kebin Liu, Yuanxin Li, Kuang Wang, Zhixi Liang, Shao Yong Zheng, Yunliang Long
Published 2020-01-01

Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation

by Hannah R. Moorman, Dakota Poschel, John D. Klement, Chunwan Lu, Priscilla S. Redd, Kebin Liu
Published 2020-11-01

p50 suppresses cytotoxic T lymphocyte effector function to regulate tumor immune escape and response to immunotherapy

by Chunwan Lu, Kebin Liu, John D Klement, Alyssa D Smith, Dafeng Yang, Darren D Browning
Published 2020-07-01

Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

by John D. Klement, Dakota B. Poschel, Chunwan Lu, Alyssa D. Merting, Dafeng Yang, Priscilla S. Redd, Kebin Liu
Published 2021-02-01

H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells

by Priscilla S. Redd, Chunwan Lu, John D. Klement, Mohammed L. Ibrahim, Gang Zhou, Takumi Kumai, Esteban Celis, Kebin Liu
Published 2018-09-01

TNFα cooperates with IFN-γ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.

by Feiyan Liu, Xiaolin Hu, Mary Zimmerman, Jennifer L Waller, Ping Wu, Andrea Hayes-Jordan, Dina Lev, Kebin Liu
Published 2011-01-01

Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes

by Chunwan Lu, John D. Klement, Mohammed L. Ibrahim, Wei Xiao, Priscilla S. Redd, Asha Nayak-Kapoor, Gang Zhou, Kebin Liu
Published 2019-06-01

Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells

by Chunwan Lu, Dafeng Yang, Maria E. Sabbatini, Aaron H. Colby, Mark W. Grinstaff, Nicholas H. Oberlies, Cedric Pearce, Kebin Liu
Published 2018-02-01

WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape

by Jennifer L Waller, Chunwan Lu, Kebin Liu, John D Klement, Dafeng Yang, Zhuoqi Liu, Alyssa D Merting, Dakota Poschel, Thomas Albers, Huidong Shi
Published 2021-07-01

IFN-γ upregulates survivin and Ifi202 expression to induce survival and proliferation of tumor-specific T cells.

by Mary Zimmerman, Dafeng Yang, Xiaolin Hu, Feiyan Liu, Nagendra Singh, Darren Browning, Vadivel Ganapathy, Phillip Chandler, Divaker Choubey, Scott I Abrams, Kebin Liu
Published 2010-11-01

Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis

by Mohammed L. Ibrahim, John D. Klement, Chunwan Lu, Priscilla S. Redd, Wei Xiao, Dafeng Yang, Darren D. Browning, Natasha M. Savage, Phillip J. Buckhaults, Herbert C. Morse, III, Kebin Liu
Published 2018-12-01

Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics

by Shuaishuai Wang, Congcong Chen, Madhusudhan Reddy Gadi, Varma Saikam, Ding Liu, He Zhu, Roni Bollag, Kebin Liu, Xi Chen, Fengshan Wang, Peng George Wang, Peixue Ling, Wanyi Guan, Lei Li
Published 2021-06-01