Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health

by Sathish Sivaprakasam, Yangzom D. Bhutia, Sabarish Ramachandran, Vadivel Ganapathy
Published 2017-08-01

SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine–Glycine–One-Carbon Pathways in Cancer

by Tyler Sneigowski, Ksenija Korac, Yangzom D. Bhutia, Vadivel Ganapathy
Published 2021-03-01

Carnitine deficiency in OCTN2-/- newborn mice leads to a severe gut and immune phenotype with widespread atrophy, apoptosis and a pro-inflammatory response.

by Srinivas Sonne, Prem S Shekhawat, Dietrich Matern, Vadivel Ganapathy, Leszek Ignatowicz
Published 2012-01-01

The amino acid transporter SLC6A14 in cancer and its potential use in chemotherapy

by Yangzom D. Bhutia, Ellappan Babu, Puttur D. Prasad, Vadivel Ganapathy
Published 2014-12-01

Pharmacologic inducers of the uric acid exporter ABCG2 as potential drugs for treatment of gouty arthritis

by Bojana Ristic, Mohd Omar Faruk Sikder, Yangzom D. Bhutia, Vadivel Ganapathy
Published 2020-03-01

Plasma Membrane Na+-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy

by Yangzom D. Bhutia, Jonathan J. Kopel, John J. Lawrence, Volker Neugebauer, Vadivel Ganapathy
Published 2017-02-01

RETRACTED ARTICLE: Identification of a novel Na+-coupled Fe3+-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells

by Jiro Ogura, Ellappan Babu, Seiji Miyauchi, Sabarish Ramachandran, Elizebeta Nemeth, Yangzom D. Bhutia, Vadivel Ganapathy
Published 2018-02-01

Transporter-Targeted Nano-Sized Vehicles for Enhanced and Site-Specific Drug Delivery

by Longfa Kou, Qing Yao, Hailin Zhang, Maoping Chu, Yangzom D. Bhutia, Ruijie Chen, Vadivel Ganapathy
Published 2020-10-01

Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types

by Longfa Kou, Longfa Kou, Yangzom D. Bhutia, Qing Yao, Zhonggui He, Jin Sun, Vadivel Ganapathy
Published 2018-01-01

OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo

by Longfa Kou, Rui Sun, Shuyi Xiao, Xiao Cui, Jin Sun, Vadivel Ganapathy, Qing Yao, Ruijie Chen
Published 2020-01-01

Selenomethionine (Se-Met) Induces the Cystine/Glutamate Exchanger SLC7A11 in Cultured Human Retinal Pigment Epithelial (RPE) Cells: Implications for Antioxidant Therapy in Aging Re...

by Sudha Ananth, Seiji Miyauchi, Muthusamy Thangaraju, Ravirajsinh N. Jadeja, Manuela Bartoli, Vadivel Ganapathy, Pamela M. Martin
Published 2021-12-01

Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy

by Longfa Kou, Qing Yao, Sathish Sivaprakasam, Qiuhua Luo, Yinghua Sun, Qiang Fu, Zhonggui He, Jin Sun, Vadivel Ganapathy
Published 2017-01-01

Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu

by Sathish Sivaprakasam, Pramodh K. Ganapathy, Mohd Omar Faruk Sikder, Moamen Elmassry, Sabarish Ramachandran, Kameswara Rao Kottapalli, Vadivel Ganapathy
Published 2019-01-01

A Proton-Coupled Transport System for β-Hydroxy-β-Methylbutyrate (HMB) in Blood–Brain Barrier Endothelial Cell Line hCMEC/D3

by Kei Higuchi, Sathish Sivaprakasam, Souad R. Sennoune, Jiro Ogura, Yangzom D. Bhutia, Ricardo Rueda, Suzette L. Pereira, Vadivel Ganapathy
Published 2021-09-01

IFN-γ upregulates survivin and Ifi202 expression to induce survival and proliferation of tumor-specific T cells.

by Mary Zimmerman, Dafeng Yang, Xiaolin Hu, Feiyan Liu, Nagendra Singh, Darren Browning, Vadivel Ganapathy, Phillip Chandler, Divaker Choubey, Scott I Abrams, Kebin Liu
Published 2010-11-01

Extracellular Citrate Fuels Cancer Cell Metabolism and Growth

by Sebastian Haferkamp, Konstantin Drexler, Marianne Federlin, Hans J. Schlitt, Mark Berneburg, Jerzy Adamski, Jerzy Adamski, Jerzy Adamski, Andreas Gaumann, Edward K. Geissler, Vadivel Ganapathy, E. Kenneth Parkinson, Maria E. Mycielska
Published 2020-12-01

Nutrient Transporter Expression in the Jejunum in Relation to Body Mass Index in Patients Undergoing Bariatric Surgery

by Brian A. Irving, G. Craig Wood, Peter N. Bennotti, Ellappan Babu, Abhishek Deshpande, Michelle R. Lent, Anthony Petrick, Jon Gabrielsen, William Strodel, Glenn S. Gerhard, Christopher D. Still, Vadivel Ganapathy, David D. K. Rolston
Published 2016-10-01

Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer

by Yangzom D. Bhutia, Jiro Ogura, Paul J. Grippo, Carolina Torres, Toshihiro Sato, Mitchell Wachtel, Sabarish Ramachandran, Ellappan Babu, Sathish Sivaprakasam, Devaraja Rajasekaran, Bradley Schniers, Nhu On, Logan Smoot, Muthusamy Thangaraju, Jaya P. Gnana-Prakasam, Vadivel Ganapathy
Published 2020-03-01