Incretin-Based Therapies for Diabetic Complications: Basic Mechanisms and Clinical Evidence

by Daiji Kawanami, Keiichiro Matoba, Kazunori Sango, Kazunori Utsunomiya
Published 2016-07-01

Targeting Redox Imbalance as an Approach for Diabetic Kidney Disease

by Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Tamotsu Yokota, Kazunori Utsunomiya, Rimei Nishimura
Published 2020-02-01

Unraveling the Role of Inflammation in the Pathogenesis of Diabetic Kidney Disease

by Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Daiji Kawanami, Kazunori Utsunomiya, Rimei Nishimura
Published 2019-07-01

The Physiology, Pathology, and Therapeutic Interventions for ROCK Isoforms in Diabetic Kidney Disease

by Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Kensuke Sekiguchi, Tamotsu Yokota, Kazunori Utsunomiya, Rimei Nishimura
Published 2020-09-01

Endothelial Dysfunction in Diabetes

by Yusuke Takeda, Keiichiro Matoba, Kensuke Sekiguchi, Yosuke Nagai, Tamotsu Yokota, Kazunori Utsunomiya, Rimei Nishimura
Published 2020-06-01

SGLT2 Inhibitors as a Therapeutic Option for Diabetic Nephropathy

by Daiji Kawanami, Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Tomoyo Akamine, Tamotsu Yokota, Kazunori Sango, Kazunori Utsunomiya
Published 2017-05-01

Renal ROCK Activation and Its Pharmacological Inhibition in Patients With Diabetes

by Keiichiro Matoba, Kensuke Sekiguchi, Yosuke Nagai, Yusuke Takeda, Hiroshi Takahashi, Tamotsu Yokota, Kazunori Utsunomiya, Rimei Nishimura
Published 2021-09-01

The thromboprotective effect of traditional Chinese medicine Tongji 2 granules is dependent on anti-inflammatory activity by suppression of NF-κB pathways.

by Lin Zhou, Stephanie Lapping, Xudong Liao, Yuan Lu, Guangjin Zhou, Keiichiro Matoba, Neelakantan Vasudevan, Lemin Wang, Lalitha Nayak
Published 2020-01-01

ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells

by Yusuke Takeda, Keiichiro Matoba, Daiji Kawanami, Yosuke Nagai, Tomoyo Akamine, Sho Ishizawa, Yasushi Kanazawa, Tamotsu Yokota, Kazunori Utsunomiya
Published 2019-03-01

Rho-Kinase Blockade Attenuates Podocyte Apoptosis by Inhibiting the Notch Signaling Pathway in Diabetic Nephropathy

by Keiichiro Matoba, Daiji Kawanami, Yosuke Nagai, Yusuke Takeda, Tomoyo Akamine, Sho Ishizawa, Yasushi Kanazawa, Tamotsu Yokota, Kazunori Utsunomiya
Published 2017-08-01

Adipose KLF15 Controls Lipid Handling to Adapt to Nutrient Availability

by Keiichiro Matoba, Yuan Lu, Rongli Zhang, Eric R. Chen, Panjamaporn Sangwung, Benlian Wang, Domenick A. Prosdocimo, Mukesh K. Jain
Published 2017-12-01

Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammation

by David R. Sweet, Neelakantan T. Vasudevan, Liyan Fan, Chloe E. Booth, Komal S. Keerthy, Xudong Liao, Vinesh Vinayachandran, Yoichi Takami, Derin Tugal, Nikunj Sharma, E. Ricky Chan, Lilei Zhang, Yulan Qing, Stanton L. Gerson, Chen Fu, Anthony Wynshaw-Boris, Panjamaporn Sangwung, Lalitha Nayak, Paul Holvoet, Keiichiro Matoba, Yuan Lu, Guangjin Zhou, Mukesh K. Jain
Published 2020-11-01