Vacuolar protein sorting protein 41 (VPS41) at an intersection of endosomal traffic in neurodegenerative disease

by Edward F Griffin, Kim A Caldwell, Guy A Caldwell
Published 2019-01-01

Modeling neurodegeneration in Caenorhabditis elegans

by Kim A. Caldwell, Corey W. Willicott, Guy A. Caldwell
Published 2020-10-01

Found in Translation: The Utility of <i>C. elegans</i> Alpha-Synuclein Models of Parkinson’s Disease

by Anthony L. Gaeta, Kim A. Caldwell, Guy A. Caldwell
Published 2019-03-01

No Country for Old Worms: A Systematic Review of the Application of <i>C. elegans</i> to Investigate a Bacterial Source of Environmental Neurotoxicity in Parkinson’s Disease

by Kim A. Caldwell, Jennifer L. Thies, Guy A. Caldwell
Published 2018-10-01

VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease

by Qingmin Ruan, Adam J. Harrington, Kim A. Caldwell, Guy A. Caldwell, David G. Standaert
Published 2010-02-01

Bcl-xL Is Required by Primary Hippocampal Neurons during Development to Support Local Energy Metabolism at Neurites

by Joseph Jansen, Madison Scott, Emma Amjad, Allison Stumpf, Kimberly H. Lackey, Kim A. Caldwell, Han-A Park
Published 2021-08-01

Genetic Defects in Mitochondrial Dynamics in <i>Caenorhabditis elegans</i> Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration

by Jessica H. Hartman, Claudia Gonzalez-Hunt, Samantha M. Hall, Ian T. Ryde, Kim A. Caldwell, Guy A. Caldwell, Joel N. Meyer
Published 2019-06-01

TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS

by Michelle L. Thompson, Pan Chen, Xiaohui Yan, Hanna Kim, Akeem R. Borom, Nathan B. Roberts, Kim A. Caldwell, Guy A. Caldwell
Published 2014-02-01

Conserved nicotine-activated neuroprotective pathways involve mitochondrial stress

by J. Brucker Nourse, Jr., Gilad Harshefi, Adi Marom, Abdelrahaman Karmi, Hagit Cohen Ben-Ami, Kim A. Caldwell, Guy A. Caldwell, Millet Treinin
Published 2021-03-01

Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease.

by Shaoxiao Wang, Siyuan Zhang, Chuan Xu, Addie Barron, Floyd Galiano, Dhaval Patel, Yong Joo Lee, Guy A Caldwell, Kim A Caldwell, Stephan N Witt
Published 2016-01-01

ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenic Caenorhabditis elegans

by Edward F. Griffin, Samuel E. Scopel, Cayman A. Stephen, Adam C. Holzhauer, Madeline A. Vaji, Ryan A. Tuckey, Laura A. Berkowitz, Kim A. Caldwell, Guy A. Caldwell
Published 2019-02-01

Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration.

by Kim A Caldwell, Michelle L Tucci, Jafa Armagost, Tyler W Hodges, Jue Chen, Shermeen B Memon, Jeana E Blalock, Susan M DeLeon, Robert H Findlay, Qingmin Ruan, Philip J Webber, David G Standaert, Julie B Olson, Guy A Caldwell
Published 2009-10-01

Therapeutic genetic variation revealed in diverse Hsp104 homologs

by Zachary M March, Katelyn Sweeney, Hanna Kim, Xiaohui Yan, Laura M Castellano, Meredith E Jackrel, JiaBei Lin, Edward Chuang, Edward Gomes, Corey W Willicott, Karolina Michalska, Robert P Jedrzejczak, Andrzej Joachimiak, Kim A Caldwell, Guy A Caldwell, Ophir Shalem, James Shorter
Published 2020-12-01

Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation

by Reini E N van der Welle, Rebekah Jobling, Christian Burns, Paolo Sanza, Jan A van der Beek, Alfonso Fasano, Lan Chen, Fried J Zwartkruis, Susan Zwakenberg, Edward F Griffin, Corlinda ten Brink, Tineke Veenendaal, Nalan Liv, Conny M A van Ravenswaaij‐Arts, Henny H Lemmink, Rolph Pfundt, Susan Blaser, Carolina Sepulveda, Andres M Lozano, Grace Yoon, Teresa Santiago‐Sim, Cedric S Asensio, Guy A Caldwell, Kim A Caldwell, David Chitayat, Judith Klumperman
Published 2021-05-01