Allostatic Changes in the cAMP System Drive Opioid-Induced Adaptation in Striatal Dopamine Signaling

by Brian S. Muntean, Maria T. Dao, Kirill A. Martemyanov
Published 2019-10-01

RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling

by Olga Ostrovskaya, Keqiang Xie, Ikuo Masuho, Ana Fajardo-Serrano, Rafael Lujan, Kevin Wickman, Kirill A Martemyanov
Published 2014-04-01

Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling

by Zhi-Xiang Xu, Ji-Wei Tan, Haifei Xu, Cassandra J. Hill, Olga Ostrovskaya, Kirill A. Martemyanov, Baoji Xu
Published 2019-08-01

Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior

by Ignacio Sarria, Johan Pahlberg, Yan Cao, Alexander V Kolesnikov, Vladimir J Kefalov, Alapakkam P Sampath, Kirill A Martemyanov
Published 2015-04-01

Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability.

by Ekaterina Posokhova, David Ng, Aaisha Opel, Ikuo Masuho, Andrew Tinker, Leslie G Biesecker, Kevin Wickman, Kirill A Martemyanov
Published 2013-01-01

The influences of the M2R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart.

by Kanchan Kulkarni, Xueyi Xie, Ezequiel Marron Fernandez de Velasco, Allison Anderson, Kirill A Martemyanov, Kevin Wickman, Elena G Tolkacheva
Published 2018-01-01

Dopamine Receptor DAMB Signals via Gq to Mediate Forgetting in Drosophila

by Sophie Himmelreich, Ikuo Masuho, Jacob A. Berry, Courtney MacMullen, Nickolas K. Skamangas, Kirill A. Martemyanov, Ronald L. Davis
Published 2017-11-01

Correction: The influences of the M2R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart.

by Kanchan Kulkarni, Xueyi Xie, Ezequiel Marron Fernandez de Velasco, Allison Anderson, Kirill A Martemyanov, Kevin Wickman, Elena G Tolkacheva
Published 2018-01-01

NF1-cAMP signaling dissociates cell type-specific contributions of striatal medium spiny neurons to reward valuation and motor control.

by Laurie P Sutton, Brian S Muntean, Olga Ostrovskaya, Stefano Zucca, Maria Dao, Cesare Orlandi, Chenghui Song, Keqiang Xie, Kirill A Martemyanov
Published 2019-10-01

Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex

by Dipak N Patil, Erumbi S Rangarajan, Scott J Novick, Bruce D Pascal, Douglas J Kojetin, Patrick R Griffin, Tina Izard, Kirill A Martemyanov
Published 2018-12-01

Expression and relevance of the G protein-gated K+ channel in the mouse ventricle

by Allison Anderson, Kanchan Kulkarni, Ezequiel Marron Fernandez de Velasco, Nicholas Carlblom, Zhilian Xia, Atsushi Nakano, Kirill A. Martemyanov, Elena G. Tolkacheva, Kevin Wickman
Published 2018-01-01

Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits

by Brian S. Muntean, Stefano Zucca, Courtney M. MacMullen, Maria T. Dao, Caitlin Johnston, Hideki Iwamoto, Randy D. Blakely, Ronald L. Davis, Kirill A. Martemyanov
Published 2018-01-01

Extended Phenotyping and Functional Validation Facilitate Diagnosis of a Complex Patient Harboring Genetic Variants in <i>MCCC1</i> and <i>GNB5</i> Causing Overlapping Phenotypes

by Zhuo Shao, Ikuo Masuho, Anupreet Tumber, Jason T. Maynes, Erika Tavares, Asim Ali, Stacy Hewson, Andreas Schulze, Peter Kannu, Kirill A. Martemyanov, Ajoy Vincent
Published 2021-08-01

Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors

by Cesare Orlandi, Yoshihiro Omori, Yuchen Wang, Yan Cao, Akiko Ueno, Michel J. Roux, Giuseppe Condomitti, Joris de Wit, Motoi Kanagawa, Takahisa Furukawa, Kirill A. Martemyanov
Published 2018-10-01

Molecular Deconvolution Platform to Establish Disease Mechanisms by Surveying GPCR Signaling

by Ikuo Masuho, Sreenivas Chavali, Brian S. Muntean, Nickolas K. Skamangas, Kristina Simonyan, Dipak N. Patil, Grant M. Kramer, Laurie Ozelius, M. Madan Babu, Kirill A. Martemyanov
Published 2018-07-01

Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D₁ and D₂ Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening

by Trevor B. Doyle, Brian S. Muntean, Karin F. Ejendal, Michael P. Hayes, Monica Soto-Velasquez, Kirill A. Martemyanov, Carmen W. Dessauer, Chang-Deng Hu, Val J. Watts
Published 2019-11-01

LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors

by Ignacio Sarria, Yan Cao, Yuchen Wang, Norianne T. Ingram, Cesare Orlandi, Naomi Kamasawa, Alexander V. Kolesnikov, Johan Pahlberg, Vladimir J. Kefalov, Alapakkam P. Sampath, Kirill A. Martemyanov
Published 2018-03-01

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

by Sahil Gulati, Hui Jin, Ikuo Masuho, Tivadar Orban, Yuan Cai, Els Pardon, Kirill A. Martemyanov, Philip D. Kiser, Phoebe L. Stewart, Christopher P. Ford, Jan Steyaert, Krzysztof Palczewski
Published 2018-05-01

Haploinsufficiency as a disease mechanism in GNB1‐associated neurodevelopmental disorder

by Laura Schultz‐Rogers, Ikuo Masuho, Filippo Pinto e Vairo, Christopher T. Schmitz, Tanya L. Schwab, Karl J. Clark, Lauren Gunderson, Pavel N. Pichurin, Klaas Wierenga, Kirill A. Martemyanov, Eric W. Klee
Published 2020-11-01

Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling

by Keqiang Xie, Ikuo Masuho, Chien-Cheng Shih, Yan Cao, Keita Sasaki, Chun Wan J Lai, Pyung-Lim Han, Hiroshi Ueda, Carmen W Dessauer, Michelle E Ehrlich, Baoji Xu, Barry M Willardson, Kirill A Martemyanov
Published 2015-11-01