Optimizing the management of intermediate-stage hepatocellular carcinoma: Current trends and prospects

by Takuji Torimura, Hideki Iwamoto
Published 2021-04-01

Second fertility preservation surgery for early relapse of seromucinous borderline ovarian tumors

by Motoko Kanno, Hideki Iwamoto, Satoshi Umezawa
Published 2021-08-01

Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT...

by Dan Nakano, Takumi Kawaguchi, Hideki Iwamoto, Masako Hayakawa, Hironori Koga, Takuji Torimura
Published 2020-01-01

Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits

by Brian S. Muntean, Stefano Zucca, Courtney M. MacMullen, Maria T. Dao, Caitlin Johnston, Hideki Iwamoto, Randy D. Blakely, Ronald L. Davis, Kirill A. Martemyanov
Published 2018-01-01

Antiangiogenic and Antitumor Activities of Aflibercept, a Soluble VEGF Receptor-1 and -2, in a Mouse Model of Hepatocellular Carcinoma

by Takuji Torimura, Hideki Iwamoto, Toru Nakamura, Mitsuhiko Abe, Yu Ikezono, Fumitaka Wada, Takahiko Sakaue, Hiroshi Masuda, Osamu Hashimoto, Hironori Koga, Takato Ueno, Hirohisa Yano
Published 2016-07-01

Therapeutic Outcomes and Prognostic Factors of Unresectable Intrahepatic Cholangiocarcinoma: A Data Mining Analysis

by Tomotake Shirono, Takashi Niizeki, Hideki Iwamoto, Shigeo Shimose, Hiroyuki Suzuki, Takumi Kawaguchi, Naoki Kamachi, Yu Noda, Shusuke Okamura, Masahito Nakano, Ryoko Kuromatu, Hironori Koga, Takuji Torimura
Published 2021-03-01

Clinical Importance of Regimens in Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma with Macrovascular Invasion

by Takashi Niizeki, Hideki Iwamoto, Tomotake Shirono, Shigeo Shimose, Masahito Nakano, Shusuke Okamura, Yu Noda, Naoki Kamachi, Suzuki Hiroyuki, Miwa Sakai, Ryoko Kuromatsu, Hironori Koga, Takuji Torimura
Published 2021-09-01

Primary Treatment with Molecular‐Targeted Agents for Hepatocellular Carcinoma: A Propensity Score‐matching Analysis

by Masahito Nakano, Ryoko Kuromatsu, Takashi Niizeki, Shusuke Okamura, Hideki Iwamoto, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Hironori Koga, Takuji Torimura, The Kurume Liver Cancer Study Group of Japan
Published 2020-08-01

Metronomic S-1 Chemotherapy and Vandetanib: An Efficacious and Nontoxic Treatment for Hepatocellular Carcinoma

by Hideki Iwamoto, Takuji Torimura, Toru Nakamura, Osamu Hashimoto, Kinya Inoue, Junichi Kurogi, Takashi Niizeki, Reiichiro Kuwahara, Mitsuhiko Abe, Hiromori Koga, Hirohisa Yano, Robert S. Kerbel, Takato Ueno, Michio Sata
Published 2011-03-01

Clinical Significance of Adverse Events for Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib: A Multicenter Retrospective Study

by Shigeo Shimose, Hideki Iwamoto, Takashi Niizeki, Tomotake Shirono, Yu Noda, Naoki Kamachi, Shusuke Okamura, Masahito Nakano, Hideya Suga, Ryoko Kuromatsu, Taizo Yamaguchi, Takumi Kawaguchi, Masatoshi Tanaka, Kazunori Noguchi, Hironori Koga, Takuji Torimura
Published 2020-07-01

Alternating Lenvatinib and Trans-Arterial Therapy Prolongs Overall Survival in Patients with Inter-Mediate Stage HepatoCellular Carcinoma: A Propensity Score Matching Study

by Shigeo Shimose, Hideki Iwamoto, Masatoshi Tanaka, Takashi Niizeki, Tomotake Shirono, Yu Noda, Naoki Kamachi, Shusuke Okamura, Masahito Nakano, Hideya Suga, Taizo Yamaguchi, Takumi Kawaguchi, Ryoko Kuromatsu, Kazunori Noguchi, Hironori Koga, Takuji Torimura
Published 2021-01-01

Controlling Nutritional Status (CONUT) Score is Associated with Overall Survival in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib: A Multicenter Cohor...

by Shigeo Shimose, Takumi Kawaguchi, Hideki Iwamoto, Masatoshi Tanaka, Ken Miyazaki, Miki Ono, Takashi Niizeki, Tomotake Shirono, Shusuke Okamura, Masahito Nakano, Hideya Suga, Taizo Yamaguchi, Yoshinori Yokokura, Kazunori Noguchi, Hironori Koga, Takuji Torimura
Published 2020-04-01

Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

by Takahiro Seki, Kayoko Hosaka, Sharon Lim, Carina Fischer, Jennifer Honek, Yunlong Yang, Patrik Andersson, Masaki Nakamura, Erik Näslund, Seppo Ylä-Herttuala, Meili Sun, Hideki Iwamoto, Xuri Li, Yizhi Liu, Nilesh J. Samani, Yihai Cao
Published 2016-08-01

Ex vivo expansion of circulating CD34+ cells enhances the regenerative effect on rat liver cirrhosis

by Toru Nakamura, Hironori Koga, Hideki Iwamoto, Victor Tsutsumi, Yasuko Imamura, Masako Naitou, Atsutaka Masuda, Yu Ikezono, Mitsuhiko Abe, Fumitaka Wada, Takahiko Sakaue, Takato Ueno, Masaaki Ii, Cantas Alev, Atsuhiko Kawamoto, Takayuki Asahara, Takuji Torimura
Published 2016-01-01

Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism

by Yunlong Yang, Yin Zhang, Hideki Iwamoto, Kayoko Hosaka, Takahiro Seki, Patrik Andersson, Sharon Lim, Carina Fischer, Masaki Nakamura, Mitsuhiko Abe, Renhai Cao, Peter Vilhelm Skov, Fang Chen, Xiaoyun Chen, Yongtian Lu, Guohui Nie, Yihai Cao
Published 2016-09-01

Inhibition of hypoxia-inducible factor via upregulation of von Hippel-Lindau protein induces âangiogenic switch offâ in a hepatoma mouse model

by Hideki Iwamoto, Toru Nakamura, Hironori Koga, Jesus Izaguirre-Carbonell, Shinji Kamisuki, Fumio Sugawara, Mitsuhiko Abe, Kazuki Iwabata, Yu Ikezono, Takahiko Sakaue, Atsutaka Masuda, Hirohisa Yano, Keisuke Ohta, Masahito Nakano, Shigeo Shimose, Tomotake Shirono, Takuji Torimura
Published 2015-01-01

Weekends-Off Lenvatinib for Unresectable Hepatocellular Carcinoma Improves Therapeutic Response and Tolerability toward Adverse Events

by Hideki Iwamoto, Hiroyuki Suzuki, Shigeo Shimose, Takashi Niizeki, Masahito Nakano, Tomotake Shirono, Shusuke Okamura, Yu Noda, Naoki Kamachi, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Dan Nakano, Miwa Sakai, Taizo Yamaguchi, Ryoko Kuromatsu, Hironori Koga, Takuji Torimura
Published 2020-04-01

Efficacy and tolerability of Sorafenib plus metronomic chemotherapy S-1 for advanced hepatocellular carcinoma in preclinical and clinical assessments

by Hiroyuki Suzuki, Hideki Iwamoto, Masahito Nakano, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Dan Nakano, Ryoko Kuromatsu, Takashi Niizeki, Shusuke Okamura, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Hirohisa Yano, Atsushi Kawaguchi, Hironori Koga, Takuji Torimura
Published 2021-11-01

Initial Experience of Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma in Real-World Clinical Practice

by Hideki Iwamoto, Shigeo Shimose, Yu Noda, Tomotake Shirono, Takashi Niizeki, Masahito Nakano, Shusuke Okamura, Naoki Kamachi, Hiroyuki Suzuki, Miwa Sakai, Akira Kajiwara, Satoshi Itano, Masatoshi Tanaka, Taizo Yamaguchi, Ryoko Kuromatsu, Hironori Koga, Takuji Torimura, on behalf of The Kurume Liver Cancer Study Group of Japan
Published 2021-06-01

The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages

by Yunlong Yang, Patrik Andersson, Kayoko Hosaka, Yin Zhang, Renhai Cao, Hideki Iwamoto, Xiaojuan Yang, Masaki Nakamura, Jian Wang, Rujie Zhuang, Hiromasa Morikawa, Yuan Xue, Harald Braun, Rudi Beyaert, Nilesh Samani, Susumu Nakae, Emily Hams, Steen Dissing, Padraic G. Fallon, Robert Langer, Yihai Cao
Published 2016-05-01