Genes associated with retinitis pigmentosa and allied diseases are frequently mutated in the general population.

by Koji M Nishiguchi, Carlo Rivolta
Published 2012-01-01

Spatially and Temporally Regulated NRF2 Gene Therapy Using Mcp-1 Promoter in Retinal Ganglion Cell Injury

by Kosuke Fujita, Koji M. Nishiguchi, Yukihiro Shiga, Toru Nakazawa
Published 2017-06-01

Single AAV-mediated mutation replacement genome editing in limited number of photoreceptors restores vision in mice

by Koji M. Nishiguchi, Kosuke Fujita, Fuyuki Miya, Shota Katayama, Toru Nakazawa
Published 2020-01-01

Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.

by Koji M Nishiguchi, Keiko Kataoka, Shu Kachi, Keiichi Komeima, Hiroko Terasaki
Published 2010-01-01

Polypoidal choroidal vasculopathy in a case of retinitis pigmentosa, successfully treated with intravitreal aflibercept

by Nana Takahashi, Hiroshi Kunikata, Masayuki Yasuda, Takehiro Hariya, Koji M. Nishiguchi, Toru Nakazawa
Published 2021-09-01

Quantitative MRI evaluation of glaucomatous changes in the visual pathway.

by Mana Fukuda, Kazuko Omodaka, Yasuko Tatewaki, Noriko Himori, Izumi Matsudaira, Koji M Nishiguchi, Takaki Murata, Yasuyuki Taki, Toru Nakazawa
Published 2018-01-01

Measurement of Electroretinograms and Visually Evoked Potentials in Awake Moving Mice.

by Yusuke Tomiyama, Kosuke Fujita, Koji M Nishiguchi, Naoyuki Tokashiki, Reiko Daigaku, Kitako Tabata, Eriko Sugano, Hiroshi Tomita, Toru Nakazawa
Published 2016-01-01

Exome sequencing of index patients with retinal dystrophies as a tool for molecular diagnosis.

by Marta Corton, Koji M Nishiguchi, Almudena Avila-Fernández, Konstantinos Nikopoulos, Rosa Riveiro-Alvarez, Sorina D Tatu, Carmen Ayuso, Carlo Rivolta
Published 2013-01-01

Correction: Exome Sequencing of Index Patients with Retinal Dystrophies as a Tool for Molecular Diagnosis.

by Marta Corton, Koji M Nishiguchi, Almudena Avila-Fernández, Konstantinos Nikopoulos, Rosa Riveiro-Alvarez, Sorina D Tatu, Carmen Ayuso, Carlo Rivolta
Published 2016-01-01

Endogenous endophthalmitis caused by group B streptococcus; case reports and review of 35 reported cases

by Masaaki Yoshida, Shunji Yokokura, Takashi Nishida, Kiyofumi Mochizuki, Takashi Suzuki, Kazuichi Maruyama, Takaaki Otomo, Koji M. Nishiguchi, Hiroshi Kunikata, Toru Nakazawa
Published 2020-03-01

Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy.

by Shinji Ueno, Koji M Nishiguchi, Hidetoshi Tanioka, Atsushi Enomoto, Takashi Yamanouchi, Mineo Kondo, Testuhiro R Yasuma, Shunsuke Yasuda, Noriyuki Kuno, Masahide Takahashi, Hiroko Terasaki
Published 2013-01-01

Analysis of Macular Drusen and Blood Test Results in 945 Macaca fascicularis.

by Koji M Nishiguchi, Yu Yokoyama, Yusuke Fujii, Kosuke Fujita, Yusuke Tomiyama, Ryo Kawasaki, Toshinori Furukawa, Fumiko Ono, Nobuhiro Shimozawa, Mutsumi Togo, Michihiro Suzuki, Toru Nakazawa
Published 2016-01-01

The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation

by Shigeto Maekawa, Kota Sato, Kosuke Fujita, Reiko Daigaku, Hiroshi Tawarayama, Namie Murayama, Satoru Moritoh, Takeshi Yabana, Yukihiro Shiga, Kazuko Omodaka, Kazuichi Maruyama, Koji M. Nishiguchi, Toru Nakazawa
Published 2017-07-01

Additive effects of genetic variants associated with intraocular pressure in primary open-angle glaucoma.

by Fumihiko Mabuchi, Nakako Mabuchi, Yoichi Sakurada, Seigo Yoneyama, Kenji Kashiwagi, Hiroyuki Iijima, Zentaro Yamagata, Mitsuko Takamoto, Makoto Aihara, Takeshi Iwata, Kazuhide Kawase, Yukihiro Shiga, Koji M Nishiguchi, Toru Nakazawa, Mineo Ozaki, Makoto Araie, Japan Glaucoma Society Omics Group (JGS-OG)
Published 2017-01-01

Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7.

by Yukihiro Shiga, Koji M Nishiguchi, Yosuke Kawai, Kaname Kojima, Kota Sato, Kosuke Fujita, Mai Takahashi, Kazuko Omodaka, Makoto Araie, Kenji Kashiwagi, Makoto Aihara, Takeshi Iwata, Fumihiko Mabuchi, Mitsuko Takamoto, Mineo Ozaki, Kazuhide Kawase, Nobuo Fuse, Masayuki Yamamoto, Jun Yasuda, Masao Nagasaki, Toru Nakazawa, Japan Glaucoma Society Omics Group (JGS-OG)
Published 2017-01-01

A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa

by Koji M. Nishiguchi, Fuyuki Miya, Yuka Mori, Kosuke Fujita, Masato Akiyama, Takashi Kamatani, Yoshito Koyanagi, Kota Sato, Toru Takigawa, Shinji Ueno, Misato Tsugita, Hiroshi Kunikata, Katarina Cisarova, Jo Nishino, Akira Murakami, Toshiaki Abe, Yukihide Momozawa, Hiroko Terasaki, Yuko Wada, Koh-Hei Sonoda, Carlo Rivolta, Tatsuhiko Tsunoda, Motokazu Tsujikawa, Yasuhiro Ikeda, Toru Nakazawa
Published 2021-01-01

Axial Spondylometaphyseal Dysplasia Is Caused by C21orf2 Mutations.

by Zheng Wang, Aritoshi Iida, Noriko Miyake, Koji M Nishiguchi, Kosuke Fujita, Toru Nakazawa, Abdulrahman Alswaid, Mohammed A Albalwi, Ok-Hwa Kim, Tae-Joon Cho, Gye-Yeon Lim, Bertrand Isidor, Albert David, Cecilie F Rustad, Else Merckoll, Jostein Westvik, Eva-Lena Stattin, Giedre Grigelioniene, Ikuyo Kou, Masahiro Nakajima, Hirohumi Ohashi, Sarah Smithson, Naomichi Matsumoto, Gen Nishimura, Shiro Ikegawa
Published 2016-01-01

A frequent variant in the Japanese population determines quasi-Mendelian inheritance of rare retinal ciliopathy

by Konstantinos Nikopoulos, Katarina Cisarova, Mathieu Quinodoz, Hanna Koskiniemi-Kuendig, Noriko Miyake, Pietro Farinelli, Atta Ur Rehman, Muhammad Imran Khan, Andrea Prunotto, Masato Akiyama, Yoichiro Kamatani, Chikashi Terao, Fuyuki Miya, Yasuhiro Ikeda, Shinji Ueno, Nobuo Fuse, Akira Murakami, Yuko Wada, Hiroko Terasaki, Koh-Hei Sonoda, Tatsuro Ishibashi, Michiaki Kubo, Frans P. M. Cremers, Zoltán Kutalik, Naomichi Matsumoto, Koji M. Nishiguchi, Toru Nakazawa, Carlo Rivolta
Published 2019-06-01