Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

by Heckl, Dirk, Kowalczyk, Monika S., Yudovich, David, Belizaire, Roger, Puram, Rishi V., McConkey, Marie, Thielke, Anne, Aster, Jon C., Regev, Aviv, Ebert, Benjamin L.
Published 2015

Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells

by Kowalczyk, Monika S., Tirosh, Itay, Heckl, Dirk, Rao, Tata Nageswara, Dixit, Atray, Haas, Brian J., Schneider, Rebekka K., Wagers, Amy J., Ebert, Benjamin L., Regev, Aviv
Published 2016

Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age

by Mann, Mati, Mehta, Arnav, de Boer, Carl G., Kowalczyk, Monika S., Lee, Kevin, Haldeman, Pearce, Rogel, Noga, Knecht, Abigail R., Farouq, Daneyal, Regev, Aviv, Baltimore, David
Published 2019

The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression

by Mehta, Arnav, Zhao, Jimmy L, Sinha, Nikita, Marinov, Georgi K, Mann, Mati, Kowalczyk, Monika S, Galimidi, Rachel P, Du, Xiaomi, Erikci, Erdem, Chowdhury, Kamal, Baltimore, David, Regev, Aviv
Published 2016

T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

by Sungnak, Waradon, Wagner, Allon, Kowalczyk, Monika S, Bod, Lloyd, Kye, Yoon-Chul, Sage, Peter T, Sharpe, Arlene H, Sobel, Raymond A, Quintana, Francisco J, Rozenblatt-Rosen, Orit, Regev, Aviv, Wang, Chao, Yosef, Nir, Kuchroo, Vijay K
Published 2021

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics

by Shekhar, Karthik, Lapan, Sylvain W., Whitney, Irene E., Tran, Nicholas M., Macosko, Evan Z., Kowalczyk, Monika, Adiconis, Xian, Levin, Joshua Z., Nemesh, James, Goldman, Melissa, McCarroll, Steven A., Cepko, Constance L., Regev, Aviv, Sanes, Joshua R.
Published 2018

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia

by Baryawno, Ninib, Przybylski, Dariusz, Kowalczyk, Monika S., Kfoury, Youmna, Severe, Nicolas, Gustafsson, Karin, Kokkaliaris, Konstantinos D., Mercier, Francois, Tabaka, Marcin, Hofree, Matan, Dionne, Danielle, Papazian, Ani, Lee, Dongjun, Ashenberg, Orr, Subramanian, Ayshwarya, Vaishnav, Eeshit Dhaval, Rozenblatt-Rosen, Orit, Regev, Aviv, Scadden, David T.
Published 2020

A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells

by Singer, Meromit, Cong, Le, Kowalczyk, Monika S., Zhang, Huiyuan, Nyman, Jackson, Sakuishi, Kaori, Kurtulus, Sema, Gennert, David, Xia, Junrong, Kwon, John Y.H, Nevin, James, Herbst, Rebecca H., Yanai, Itai, Rozenblatt-Rosen, Orit, Kuchroo, Vijay K., Anderson, Ana C., Marjanovic, Nemanja, Regev, Aviv, Wang, Chao
Published 2018

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

by Puram, Rishi V, Kowalczyk, Monika S, de Boer, Carl G, Schneider, Rebekka K, Miller, Peter G, McConkey, Marie, Tothova, Zuzana, Tejero, Héctor, Heckl, Dirk, Järås, Marcus, Chen, Michelle C, Li, Hubo, Tamayo, Alfred, Cowley, Glenn S, Rozenblatt-Rosen, Orit, Al-Shahrour, Fatima, Ebert, Benjamin L, Regev, Aviv
Published 2018

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation

by Wallrapp, Antonia, Riesenfeld, Samantha J., Burkett, Patrick R., Abdulnour, Raja-Elie E., Nyman, Jackson, Dionne, Danielle, Hofree, Matan, Cuoco, Michael S., Rodman, Christopher, Farouq, Daneyal, Haas, Brian J., Tickle, Timothy L., Trombetta, John J., Baral, Pankaj, Klose, Christoph S. N., Mahlakõiv, Tanel, Artis, David, Rozenblatt-Rosen, Orit, Chiu, Isaac M., Levy, Bruce D., Kowalczyk, Monika S., Regev, Aviv, Kuchroo, Vijay K.
Published 2018

Distinct subnetworks of the thalamic reticular nucleus

by Li, Yinqing, Lopez Huerta, Violeta, Adiconis, Xian, Levandowski, Kirsten, Choi, Soonwook, Simmons, Sean K., Arias-Garcia, Mario A., Guo, Baolin, Yao, Annie, Blosser, Timothy R., Wimmer, Ralf D, Aida, Tomomi, Atamian, Alexander, Naik, Tina, Sun, Xuyun, Bi, Dasheng, Malhotra, Diya, Hession, Cynthia C., Shema Tirosh, Reut, Gomes, Marcos, Li, Taibo, Hwang, Eunjin, Krol, Alexandra, Kowalczyk, Monika, Peça, João, Pan, Gang, Halassa, Michael, Levin, Joshua Z., Fu, Zhanyan, Feng, Guoping
Published 2021

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

by Jerby-Arnon, Livnat, Shah, Parin, Cuoco, Michael S., Rodman, Christopher, Su, Mei-Ju, Melms, Johannes C., Leeson, Rachel, Kanodia, Abhay, Mei, Shaolin, Lin, Jia-Ren, Wang, Shu, Rabasha, Bokang, Liu, David, Zhang, Gao, Margolais, Claire, Ashenberg, Orr, Ott, Patrick A., Buchbinder, Elizabeth I., Haq, Rizwan, Hodi, F. Stephen, Boland, Genevieve M., Sullivan, Ryan J., Frederick, Dennie T., Miao, Benchun, Moll, Tabea, Flaherty, Keith T., Herlyn, Meenhard, Jenkins, Russell W., Thummalapalli, Rohit, Kowalczyk, Monika S., Cañadas, Israel, Schilling, Bastian, Cartwright, Adam N.R, Luoma, Adrienne M., Malu, Shruti, Hwu, Patrick, Bernatchez, Chantale, Forget, Marie-Andrée, Barbie, David A., Shalek, Alex K., Tirosh, Itay, Sorger, Peter K., Wucherpfennig, Kai, Van Allen, Eliezer M., Schadendorf, Dirk, Johnson, Bruce E., Rotem, Asaf, Rozenblatt-Rosen, Orit, Garraway, Levi A., Yoon, Charles H., Izar, Benjamin, Regev, Aviv
Published 2020

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

by Keskin, Derin B., Anandappa, Annabelle J., Sun, Jing, Tirosh, Itay, Mathewson, Nathan D., Li, Shuqiang, Oliveira, Giacomo, Giobbie-Hurder, Anita, Felt, Kristen, Gjini, Evisa, Shukla, Sachet A., Hu, Zhuting, Li, Letitia, Le, Phuong M., Allesøe, Rosa L., Richman, Alyssa R., Kowalczyk, Monika S., Abdelrahman, Sara, Geduldig, Jack E., Charbonneau, Sarah, Pelton, Kristine, Iorgulescu, J. Bryan, Elagina, Liudmila, Zhang, Wandi, Olive, Oriol, McCluskey, Christine, Olsen, Lars R., Stevens, Jonathan, Lane, William J., Salazar, Andres M., Daley, Heather, Wen, Patrick Y., Chiocca, E. Antonio, Harden, Maegan, Lennon, Niall, Gabriel, Stacey, Getz, Gad Asher, Lander, Eric Steven, Regev, Aviv, Ritz, Jerome, Neuberg, Donna, Rodig, Scott J., Ligon, Keith L., Suvà, Mario L., Wucherpfennig, Kai W., Hacohen, Nir, Fritsch, Edward F., Livak, Kenneth J., Ott, Patrick A., Wu, Catherine J., Reardon, David A.
Published 2020