MASTL inhibition promotes mitotic catastrophe through PP2A activation to inhibit cancer growth and radioresistance in breast cancer cells

by Yi Na Yoon, Min Ho Choe, Kwan-Young Jung, Sang-Gu Hwang, Jeong Su Oh, Jae-Sung Kim
Published 2018-07-01

Synthesis and Structure–Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research

by Minjin Yoo, Tae Hyun Park, Miyoun Yoo, Yeongrin Kim, Joo-Youn Lee, Kyu Myung Lee, Seong Eon Ryu, Byung Il Lee, Kwan-Young Jung, Chi Hoon Park
Published 2021-03-01

Discovery and Characterization of a Novel MASTL Inhibitor MKI-2 Targeting MASTL-PP2A in Breast Cancer Cells and Oocytes

by Minsung Kang, Chijung Kim, Jiyeon Leem, Ye-hyun Kim, Young-ju Kwon, Yi Na Yoon, Chong Hak Chae, Jiyeon Ahn, Kwan-Young Jung, Jeong Su Oh, Jae-Sung Kim
Published 2021-07-01

MKI-1, a Novel Small-Molecule Inhibitor of MASTL, Exerts Antitumor and Radiosensitizer Activities Through PP2A Activation in Breast Cancer

by Ah-Young Kim, Yi Na Yoon, Yi Na Yoon, Jiyeon Leem, Jee-Young Lee, Kwan-Young Jung, Minsung Kang, Jiyeon Ahn, Sang-Gu Hwang, Jeong Su Oh, Jae-Sung Kim, Jae-Sung Kim
Published 2020-09-01

A Novel Way of Preventing Postoperative Pancreatic Fistula by Directly Injecting Profibrogenic Materials into the Pancreatic Parenchyma

by Sang Chul Lee, Tae Ho Hong, Ok-Hee Kim, Suk Joon Cho, Kee-Hwan Kim, Jin Sook Song, Kyu-Seok Hwang, Jae-Kyung Jung, Ha-Eun Hong, Haeyeon Seo, Ho Joong Choi, Joseph Ahn, Tae Yoon Lee, Eunyoung Rim, Kwan-Young Jung, Say-June Kim
Published 2020-03-01

Efficacy and safety of a novel topical agent for gallstone dissolution: 2-methoxy-6-methylpyridine

by Ho Joong Choi, Suk Joon Cho, Ok-Hee Kim, Jin Sook Song, Ha-Eun Hong, Sang Chul Lee, Kee-Hwan Kim, Sang Kuon Lee, Young Kyoung You, Tae Ho Hong, Eun Young Kim, Jung Hyun Park, Gun Hyung Na, Dong Do You, Jae Hyun Han, Jae Woo Park, Bong Jun Kwak, Tae Yun Lee, Joseph Ahn, Hwan Hee Lee, Seung Kyu Kang, Kyu-Seok Hwang, Jae-Kyung Jung, Kwan-Young Jung, Say-June Kim
Published 2019-06-01