O renascimento de um fármaco: talidomida The rebirth of a drug: thalidomide

by Lídia Moreira Lima, Carlos Alberto Manssour Fraga, Eliezer J. Barreiro
Published 2001-10-01

Mutagenicity of New Lead Compounds to Treat Sickle Cell Disease Symptoms in a Salmonella/Microsome Assay

by Chung Man Chin, Lídia Moreira Lima, Eliana A. Varanda, Jean Leandro dos Santos
Published 2010-02-01

Assessment of the In Vivo Genotoxicity of New Lead Compounds to Treat Sickle Cell Disease

by Man Chin Chung, Lídia Moreira Lima, Jean Leandro dos Santos, Eliana Aparecida Varanda, Priscila Longhin Bosquesi
Published 2011-04-01

Therapeutic approaches for tumor necrosis factor inhibition

by Maria Letícia de Castro Barbosa, Milla Machado Fumian, Ana Luísa Palhares de Miranda, Eliezer J. Barreiro, Lídia Moreira Lima
Published 2011-09-01

3-Aminothiophene-2-Acylhydrazones: Non-Toxic, Analgesic and Anti-Inflammatory Lead-Candidates

by Yolanda Karla Cupertino da Silva, Christian Tadeo Moreno Reyes, Gildardo Rivera, Marina Amaral Alves, Eliezer J. Barreiro, Magna Suzana Alexandre Moreira, Lídia Moreira Lima
Published 2014-06-01

Synthesis and Pharmacological Evaluation of Novel Phenyl Sulfonamide Derivatives Designed as Modulators of Pulmonary Inflammatory Response

by Lídia Moreira Lima, Eliezer J. Barreiro, Marco Aurélio Martins, Patrícia Machado Rodrigues e Silva, Thiago José Figueira Ramos, Ana Carolina Santos de Arantes, Maria Letícia de Castro Barbosa
Published 2012-12-01

Analgesic and Anti-Inflammatory Activities of Salicylaldehyde 2-Chlorobenzoyl Hydrazone (H2LASSBio-466), Salicylaldehyde 4-Chlorobenzoyl Hydrazone (H2LASSBio-1064) and Their Zinc(I...

by Eliezer J. Barreiro, Heloisa Beraldo, Lídia Moreira Lima, Gabrieli L. Parrilha, Eduardo E. Castellano, Oscar E. Piro, Walfrido Bispo Júnior, Magna S. Alexandre-Moreira, Marina A. Alves, Anayive Perez-Rebolledo
Published 2011-08-01

Natural products as new antimitotic compounds for anticancer drug development

by Carlos Roberto Koscky Paier, Sarah Sant’Anna Maranhão, Teiliane Rodrigues Carneiro, Lídia Moreira Lima, Danilo Damasceno Rocha, Renan da Silva Santos, Kaio Moraes de Farias, Manoel Odorico de Moraes-Filho, Claudia Pessoa
Published 2018-12-01

Design, Synthesis, Antinociceptive and Anti-Inflammatory Activities of Novel Piroxicam Analogues

by Eliezer J. Barreiro, Lídia Moreira Lima, Rosane de Paula Castro, José Ricardo Sabino, Luciano Morais Lião, Magna Suzana Alexandre-Moreira, Walfrido Bispo Júnior, Yolanda Karla Cupertino da Silva, Amanda Silva de Miranda
Published 2012-11-01

Design and Synthesis In Silico Drug-like Prediction and Pharmacological Evaluation of Cyclopolymethylenic Homologous of LASSBio-1514

by Lidia Moreira Lima, Tiago Fernandes da Silva, Carlos Eduardo da Silva Monteiro, Cristiane Aparecida-Silva, Walfrido Bispo Júnior, Aline Cavalcanti de Queiroz, Magna Suzana Alexandre-Moreira, Gisele Zapata-Sudo, Eliezer J. Barreiro
Published 2021-08-01

Synthesis, Pharmacological Profile and Docking Studies of New Sulfonamides Designed as Phosphodiesterase-4 Inhibitors.

by Isabelle Karine da Costa Nunes, Everton Tenório de Souza, Suzana Vanessa S Cardozo, Vinicius de Frias Carvalho, Nelilma Correia Romeiro, Patrícia Machado Rodrigues E Silva, Marco Aurélio Martins, Eliezer J Barreiro, Lídia Moreira Lima
Published 2016-01-01

Novel Orally Active Analgesic and Anti-Inflammatory Cyclohexyl-N-Acylhydrazone Derivatives

by Tiago Fernandes da Silva, Walfrido Bispo Júnior, Magna Suzana Alexandre-Moreira, Fanny Nascimento Costa, Carlos Eduardo da Silva Monteiro, Fabio Furlan Ferreira, Regina Cely Rodrigues Barroso, François Noël, Roberto Takashi Sudo, Gisele Zapata-Sudo, Lídia Moreira Lima, Eliezer J. Barreiro
Published 2015-02-01

Docking, synthesis and antiproliferative activity of N-acylhydrazone derivatives designed as combretastatin A4 analogues.

by Daniel Nascimento do Amaral, Bruno C Cavalcanti, Daniel P Bezerra, Paulo Michel P Ferreira, Rosane de Paula Castro, José Ricardo Sabino, Camila Maria Longo Machado, Roger Chammas, Claudia Pessoa, Carlos M R Sant'Anna, Eliezer J Barreiro, Lídia Moreira Lima
Published 2014-01-01

LASSBio-1586, an N-acylhydrazone derivative, attenuates nociceptive behavior and the inflammatory response in mice.

by Juliane Cabral Silva, Raimundo Gonçalves de Oliveira Júnior, Mariana Gama E Silva, Érica Martins de Lavor, Juliana Mikaelly Dias Soares, Sarah Raquel Gomes de Lima-Saraiva, Tâmara Coimbra Diniz, Rosemairy Luciane Mendes, Edilson Beserra de Alencar Filho, Eliezer Jesus de Lacerda Barreiro, Lídia Moreira Lima, Jackson Roberto Guedes da Silva Almeida
Published 2018-01-01

Respiratory and Systemic Effects of LASSBio596 Plus Surfactant in Experimental Acute Respiratory Distress Syndrome

by Johnatas Dutra Silva, Gisele Pena de Oliveira, Cynthia dos Santos Samary, Carla Cristina Araujo, Gisele de Araujo Padilha, Fernando Costa e Silva Filho, Rosilane Taveira da Silva, Marcelo Einicker-Lamas, Marcelo Marcos Morales, Vera Luiza Capelozzi, Vanessa Martins da Silva, Lídia Moreira Lima, Eliezer Jesus Barreiro, Bruno Lourenço Diaz, Paolo Pelosi, Pedro Leme Silva, Cristiane Souza Nascimento Baez Garcia, Patricia Rieken Macedo Rocco
Published 2016-02-01