Francisella tularensis Vaccines Elicit Concurrent Protective T- and B-Cell Immune Responses in BALB/cByJ Mice.

by Roberto De Pascalis, Lara Mittereder, Alicia Y Chou, Nikki J Kennett, Karen L Elkins
Published 2015-01-01

Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9.

by Roberto De Pascalis, Amy P Rossi, Lara Mittereder, Kazuyo Takeda, Adovi Akue, Sherry L Kurtz, Karen L Elkins
Published 2020-01-01

A panel of correlates predicts vaccine-induced protection of rats against respiratory challenge with virulent Francisella tularensis.

by Roberto De Pascalis, Andrew Hahn, Helen M Brook, Patrik Ryden, Nathaniel Donart, Lara Mittereder, Blake Frey, Terry H Wu, Karen L Elkins
Published 2018-01-01