The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.

by Jatin Roper, Michael P Richardson, Wei Vivian Wang, Larissa Georgeon Richard, Wei Chen, Erin M Coffee, Mark J Sinnamon, Lydia Lee, Peng-Chieh Chen, Roderick T Bronson, Eric S Martin, Kenneth E Hung
Published 2011-01-01

PKM2 is not required for colon cancer initiated by APC loss

by Allison N. Lau, William J. Israelsen, Jatin Roper, Mark J. Sinnamon, Larissa Georgeon, Talya L. Dayton, Alissandra L. Hillis, Omer H. Yilmaz, Dolores Di Vizio, Kenneth E. Hung, Matthew G. Vander Heiden
Published 2017-11-01