In Vivo Optical Molecular Imaging of Matrix Metalloproteinase Activity following Celecoxib Therapy for Colorectal Cancer

by Rahul A. Sheth, Alexandra Kunin, Lars Stangenberg, Mark Sinnamon, Kenneth E. Hung, Raju Kucherlapati, Umar Mahmood
Published 2012-09-01

The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.

by Jatin Roper, Michael P Richardson, Wei Vivian Wang, Larissa Georgeon Richard, Wei Chen, Erin M Coffee, Mark J Sinnamon, Lydia Lee, Peng-Chieh Chen, Roderick T Bronson, Eric S Martin, Kenneth E Hung
Published 2011-01-01

PKM2 is not required for colon cancer initiated by APC loss

by Allison N. Lau, William J. Israelsen, Jatin Roper, Mark J. Sinnamon, Larissa Georgeon, Talya L. Dayton, Alissandra L. Hillis, Omer H. Yilmaz, Dolores Di Vizio, Kenneth E. Hung, Matthew G. Vander Heiden
Published 2017-11-01

Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease

by Peter J. Belmont, Eva Budinska, Ping Jiang, Mark J. Sinnamon, Erin Coffee, Jatin Roper, Tao Xie, Paul A. Rejto, Sahra Derkits, Owen J. Sansom, Mauro Delorenzi, Sabine Tejpar, Kenneth E. Hung, Eric S. Martin
Published 2014-06-01