Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer

by Jeroen Declercq, Bart Jacobs, Bart Biesmans, Arnaud Roth, Dirk Klingbiel, Sabine Tejpar, John W. Creemers
Published 2015-01-01

Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data.

by Ida Kappel Buhl, Sarah Gerster, Mauro Delorenzi, Thomas Jensen, Peter Buhl Jensen, Fred Bosman, Sabine Tejpar, Arnaud Roth, Nils Brunner, Anker Hansen, Steen Knudsen
Published 2016-01-01

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

by Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Abhishek D. Garg
Published 2020-01-01

Neutrophils suppress tumor‐infiltrating T cells in colon cancer via matrix metalloproteinase‐mediated activation of TGFβ

by Markus Germann, Nadine Zangger, Marc‐Olivier Sauvain, Christine Sempoux, Amber D Bowler, Pratyaksha Wirapati, Lana E Kandalaft, Mauro Delorenzi, Sabine Tejpar, George Coukos, Freddy Radtke
Published 2020-01-01

miR-345 in metastatic colorectal cancer: a non-invasive biomarker for clinical outcome in non-KRAS mutant patients treated with 3rd line cetuximab and irinotecan.

by Jakob V Schou, Simona Rossi, Benny V Jensen, Dorte L Nielsen, Per Pfeiffer, Estrid Høgdall, Mette Yilmaz, Sabine Tejpar, Mauro Delorenzi, Mogens Kruhøffer, Julia S Johansen
Published 2014-01-01

Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers.

by Nicky D'Haene, Marie Le Mercier, Nancy De Nève, Oriane Blanchard, Mélanie Delaunoy, Hakim El Housni, Barbara Dessars, Pierre Heimann, Myriam Remmelink, Pieter Demetter, Sabine Tejpar, Isabelle Salmon
Published 2015-01-01

Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids.

by Els Robanus-Maandag, Cathy Bosch, Saeid Amini-Nik, Jeroen Knijnenburg, Karoly Szuhai, Pascale Cervera, Raymond Poon, Diana Eccles, Paolo Radice, Marco Giovannini, Benjamin A Alman, Sabine Tejpar, Peter Devilee, Riccardo Fodde
Published 2011-01-01

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer.

by Salvatore Siena, Eric Van Cutsem, Mingyu Li, Ulf Jungnelius, Alfredo Romano, Robert Beck, Katia Bencardino, Maria Elena Elez, Hans Prenen, Mireia Sanchis, Andrea Sartore-Bianchi, Sabine Tejpar, Anita Gandhi, Tao Shi, Josep Tabernero
Published 2013-01-01

Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease

by Peter J. Belmont, Eva Budinska, Ping Jiang, Mark J. Sinnamon, Erin Coffee, Jatin Roper, Tao Xie, Paul A. Rejto, Sahra Derkits, Owen J. Sansom, Mauro Delorenzi, Sabine Tejpar, Kenneth E. Hung, Eric S. Martin
Published 2014-06-01

Establishing a Unified COVID-19 “Immunome”: Integrating Coronavirus Pathogenesis and Host Immunopathology

by Els Wauters, Karin Thevissen, Carine Wouters, Carine Wouters, Francesca Maria Bosisio, Frederik De Smet, Jan Gunst, Stephanie Humblet-Baron, Diether Lambrechts, Adrian Liston, Patrick Matthys, Johan Neyts, Paul Proost, Birgit Weynand, Joost Wauters, Sabine Tejpar, Abhishek D. Garg
Published 2020-07-01

A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.

by Tao Xie, Giovanni D' Ario, John R Lamb, Eric Martin, Kai Wang, Sabine Tejpar, Mauro Delorenzi, Fred T Bosman, Arnaud D Roth, Pu Yan, Stephanie Bougel, Antonio Fabio Di Narzo, Vlad Popovici, Eva Budinská, Mao Mao, Scott L Weinrich, Paul A Rejto, J Graeme Hodgson
Published 2012-01-01

Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal AdenocarcinomasSummary

by Lochlan Fennell, Troy Dumenil, Leesa Wockner, Gunter Hartel, Katia Nones, Catherine Bond, Jennifer Borowsky, Cheng Liu, Diane McKeone, Lisa Bowdler, Grant Montgomery, Kerenaftali Klein, Isabell Hoffmann, Ann-Marie Patch, Stephen Kazakoff, John Pearson, Nicola Waddell, Pratyaksha Wirapati, Paul Lochhead, Yu Imamura, Shuji Ogino, Renfu Shao, Sabine Tejpar, Barbara Leggett, Vicki Whitehall
Published 2019-01-01

Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer

by Karen Gambaro, Maud Marques, Suzan McNamara, Mathilde Couetoux du Tertre, Zuanel Diaz, Cyrla Hoffert, Archana Srivastava, Steven Hébert, Benoit Samson, Bernard Lespérance, Yoo‐Joung Ko, Richard Dalfen, Eve St‐Hilaire, Lucas Sideris, Felix Couture, Ronald Burkes, Mohammed Harb, Errol Camlioglu, Adrian Gologan, Vincent Pelsser, André Constantin, Celia M.T. Greenwood, Sabine Tejpar, Petr Kavan, Claudia L. Kleinman, Gerald Batist
Published 2021-04-01

Prevalence of Germline Pathogenic Variants in Cancer Predisposing Genes in Czech and Belgian Pancreatic Cancer Patients

by Greet Wieme, Jan Kral, Toon Rosseel, Petra Zemankova, Bram Parton, Michal Vocka, Mattias Van Heetvelde, Petra Kleiblova, Bettina Blaumeiser, Jana Soukupova, Jenneke van den Ende, Petr Nehasil, Sabine Tejpar, Marianna Borecka, Encarna B. Gómez García, Marinus J. Blok, Marketa Safarikova, Marta Kalousova, Karen Geboes, Robin De Putter, Bruce Poppe, Kim De Leeneer, Zdenek Kleibl, Marketa Janatova, Kathleen B. M. Claes
Published 2021-09-01

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis

by Joshua D. G. Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A. Ridgway, Dustin J. Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G. Vázquez, David F. Vincent, William J. Faller, Michael C. Hodder, Alexander Raven, Sigrid Fey, Arafath K. Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, S:CORT consortium, Sander R. van Hooff, David J. Huels, Jan Paul Medema, Simon T. Barry, Margaret C. Frame, Asier Unciti-Broceta, Simon J. Leedham, Gareth J. Inman, Rene Jackstadt, Barry J. Thompson, Andrew D. Campbell, Sabine Tejpar, Owen J. Sansom
Published 2021-06-01