Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

by Monia Guidi, Thomas Mercier, Manel Aouri, Laurent A. Decosterd, Chantal Csajka, Bernhards Ogutu, Gwénaëlle Carn, Jean-René Kiechel
Published 2019-04-01

The Steps to Therapeutic Drug Monitoring: A Structured Approach Illustrated With Imatinib

by Thierry Buclin, Yann Thoma, Nicolas Widmer, Nicolas Widmer, Nicolas Widmer, Pascal André, Monia Guidi, Monia Guidi, Chantal Csajka, Chantal Csajka, Laurent A. Decosterd
Published 2020-03-01

Sultiame pharmacokinetic profile in plasma and erythrocytes after single oral doses: A pilot study in healthy volunteers

by Kim Dao, Paul Thoueille, Laurent A. Decosterd, Thomas Mercier, Monia Guidi, Carine Bardinet, Sébastien Lebon, Eva Choong, Arnaud Castang, Catherine Guittet, Luc‐André Granier, Thierry Buclin
Published 2020-02-01

Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy

by Elinam Gayi, Laurence A. Neff, Xènia Massana Muñoz, Hesham M. Ismail, Marta Sierra, Thomas Mercier, Laurent A. Décosterd, Jocelyn Laporte, Belinda S. Cowling, Olivier M. Dorchies, Leonardo Scapozza
Published 2018-11-01

Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and f...

by Dany Spaggiari, Vincent Desfontaine, Sandra Cruchon, Sylvie Guinchard, Anthony Vocat, Emilyne Blattes, Jeff Pitteloud, Lorenzo Ciullini, Carine Bardinet, Anton Ivanyuk, Vadim Makarov, Olga Ryabova, Thierry Buclin, Stewart T Cole, Laurent A Decosterd
Published 2019-01-01

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

by Vadim Makarov, Benoit Lechartier, Ming Zhang, João Neres, Astrid M van derSar, Susanne A Raadsen, Ruben C Hartkoorn, Olga B Ryabova, Anthony Vocat, Laurent A Decosterd, Nicolas Widmer, Thierry Buclin, Wilbert Bitter, Koen Andries, Florence Pojer, Paul J Dyson, Stewart T Cole
Published 2014-03-01

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority S...

by Delphine Sculier, Gilles Wandeler, Sabine Yerly, Annalisa Marinosci, Marcel Stoeckle, Enos Bernasconi, Dominique L Braun, Pietro Vernazza, Matthias Cavassini, Marta Buzzi, Karin J Metzner, Laurent A Decosterd, Huldrych F Günthard, Patrick Schmid, Andreas Limacher, Matthias Egger, Alexandra Calmy, Swiss HIV Cohort Study (SHCS)
Published 2020-11-01

Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers

by Antonia E. Schantl, Anja Verhulst, Ellen Neven, Geert J. Behets, Patrick C. D’Haese, Marc Maillard, David Mordasini, Olivier Phan, Michel Burnier, Dany Spaggiari, Laurent A. Decosterd, Mark G. MacAskill, Carlos J. Alcaide-Corral, Adriana A. S. Tavares, David E. Newby, Victoria C. Beindl, Roberto Maj, Anne Labarre, Chrismita Hegde, Bastien Castagner, Mattias E. Ivarsson, Jean-Christophe Leroux
Published 2020-02-01