Biomarkers and Preclinical Models for Adult T-Cell Leukemia-Lymphoma Treatment

by Lee Ratner
Published 2019-09-01

Targeting HTLV-1 Activation of NFκB in Mouse Models and ATLL Patients

by Lee Ratner, Daniel A. Rauch
Published 2011-06-01

Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step.

by Brooke Harmon, Nancy Campbell, Lee Ratner
Published 2010-06-01

IL-15 deficient tax mice reveal a role for IL-1α in tumor immunity.

by Daniel A Rauch, John C Harding, Lee Ratner
Published 2014-01-01

Targeting NF-κB with Nanotherapy in a Mouse Model of Adult T-Cell Leukemia/Lymphoma

by Daniel A. Rauch, John C. Harding, Lee Ratner, Samuel A. Wickline, Hua Pan
Published 2021-06-01

Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency

by George B. Kyei, Shanshan Meng, Rashmi Ramani, Austin Niu, Chandraiah Lagisetti, Thomas R. Webb, Lee Ratner
Published 2018-11-01

HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1.

by Jacob Al-Saleem, Wessel P Dirksen, Michael P Martinez, Nikoloz Shkriabai, Mamuka Kvaratskhelia, Lee Ratner, Patrick L Green
Published 2019-01-01

Molecular Determinants of Human T-lymphotropic Virus Type 1 Transmission and Spread

by Patrick L. Green, Nadine Bowden, Michael D. Lairmore, Lee Ratner, Rashade A. H. Haynes II, Robyn Haines, Rajaneesh Anupam
Published 2011-07-01

Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways.

by Christian Grant, Unsong Oh, Kazunori Fugo, Norihiro Takenouchi, Caitlin Griffith, Karen Yao, Timothy E Newhook, Lee Ratner, Steven Jacobson
Published 2006-04-01

HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo

by Michael P. Martinez, Xiaogang Cheng, Ancy Joseph, Jacob Al-Saleem, Amanda R. Panfil, Marilly Palettas, Wessel P. Dirksen, Lee Ratner, Patrick L. Green
Published 2019-12-01

Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma

by Daniel A. Rauch, Sydney L. Olson, John C. Harding, Hemalatha Sundaramoorthi, Youngsoo Kim, Tianyuan Zhou, A. Robert MacLeod, Grant Challen, Lee Ratner
Published 2020-08-01

Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation

by Brice J. Albert, Austin Niu, Rashmi Ramani, Garland R. Marshall, Paul A. Wender, Robert M. Williams, Lee Ratner, Alexander B. Barnes, George B. Kyei
Published 2017-08-01

Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling.

by Rajeshree Pujari, Richard Hunte, Remy Thomas, Louise van der Weyden, Dan Rauch, Lee Ratner, Jennifer K Nyborg, Juan Carlos Ramos, Yoshimi Takai, Noula Shembade
Published 2015-03-01

Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma.

by Lee Ratner, William Harrington, Xuan Feng, Christian Grant, Steve Jacobson, Ariela Noy, Joseph Sparano, Jeannette Lee, Richard Ambinder, Nancy Campbell, Michael Lairmore, AIDS Malignancy Consortium
Published 2009-01-01

PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice.

by Eléonore Pérès, Juliana Blin, Emiliano P Ricci, Maria Artesi, Vincent Hahaut, Anne Van den Broeke, Antoine Corbin, Louis Gazzolo, Lee Ratner, Pierre Jalinot, Madeleine Duc Dodon
Published 2018-03-01

The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.

by Daniel A Rauch, Michelle A Hurchla, John C Harding, Hongju Deng, Lauren K Shea, Mark C Eagleton, Stefan Niewiesk, Michael D Lairmore, David Piwnica-Worms, Thomas J Rosol, Jason D Weber, Lee Ratner, Katherine N Weilbaecher
Published 2010-12-01

Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases

by Marcia Bellon, Izabela Bialuk, Veronica Galli, Xue-Tao Bai, Lourdes Farre, Achilea Bittencourt, Ambroise Marçais, Michael N. Petrus, Lee Ratner, Thomas A. Waldmann, Vahid Asnafi, Antoine Gessain, Masao Matsuoka, Genoveffa Franchini, Olivier Hermine, Toshiki Watanabe, Christophe Nicot
Published 2021-06-01

Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF.

by Xiaogang Cheng, Ancy Joseph, Victor Castro, Alice Chen-Liaw, Zachary Skidmore, Takaharu Ueno, Jun-Ichi Fujisawa, Daniel A Rauch, Grant A Challen, Michael P Martinez, Patrick Green, Malachi Griffith, Jacqueline E Payton, John R Edwards, Lee Ratner
Published 2021-05-01