Mutational Evolution in Relapsed Diffuse Large B-Cell Lymphoma

by Marcel Nijland, Annika Seitz, Martijn Terpstra, Gustaaf W. van Imhoff, Philip M Kluin, Tom van Meerten, Çiğdem Atayar, Léon C. van Kempen, Arjan Diepstra, Klaas Kok, Anke van den Berg
Published 2018-11-01

Comparison of Circulating Cell-Free DNA Extraction Methods for Downstream Analysis in Cancer Patients

by Paul van der Leest, Pieter A. Boonstra, Arja ter Elst, Léon C. van Kempen, Marco Tibbesma, Jill Koopmans, Anneke Miedema, Menno Tamminga, Harry J. M. Groen, Anna K. L. Reyners, Ed Schuuring
Published 2020-05-01

A Nationwide Study on the Impact of Routine Testing for <i>EGFR</i> Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on <i>EGFR</i> Mutation Subclasses

by Bart Koopman, Betzabel N. Cajiao Garcia, Chantal C. H. J. Kuijpers, Ronald A. M. Damhuis, Anthonie J. van der Wekken, Harry J. M. Groen, Ed Schuuring, Stefan M. Willems, Léon C. van Kempen
Published 2021-07-01

Peripheral and local predictive immune signatures identified in a phase II trial of ipilimumab with carboplatin/paclitaxel in unresectable stage III or stage IV melanoma

by Rahima Jamal, Réjean Lapointe, Eftihia Cocolakis, Paméla Thébault, Shirin Kazemi, Jennifer E. Friedmann, Jeanne Dionne, Jean-François Cailhier, Karl Bélanger, Jean-Pierre Ayoub, Huy Le, Caroline Lambert, Jida El-Hajjar, Léon C. van Kempen, Alan Spatz, Wilson H. Miller
Published 2017-11-01

Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation

by Pierre-Eric Lutz, Marc-Aurèle Chay, Alain Pacis, Gary G. Chen, Zahia Aouabed, Elisabetta Maffioletti, Jean-François Théroux, Jean-Christophe Grenier, Jennie Yang, Maria Aguirre, Carl Ernst, Adriana Redensek, Léon C. van Kempen, Ipek Yalcin, Tony Kwan, Naguib Mechawar, Tomi Pastinen, Gustavo Turecki
Published 2021-02-01

Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material

by Elisabeth M. P. Steeghs, Leonie I. Kroeze, Bastiaan B. J. Tops, Leon C. van Kempen, Arja ter Elst, Annemiek W. M. Kastner-van Raaij, Sandra J. B. Hendriks-Cornelissen, Mandy J. W. Hermsen, Erik A. M. Jansen, Petra M. Nederlof, Ed Schuuring, Marjolijn J. L. Ligtenberg, Astrid Eijkelenboom
Published 2020-04-01

Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing

by Amin Allahyar, Mark Pieterse, Joost Swennenhuis, G. Tjitske Los-de Vries, Mehmet Yilmaz, Roos Leguit, Ruud W. J. Meijers, Robert van der Geize, Joost Vermaat, Arjen Cleven, Tom van Wezel, Arjan Diepstra, Léon C. van Kempen, Nathalie J. Hijmering, Phylicia Stathi, Milan Sharma, Adrien S. J. Melquiond, Paula J. P. de Vree, Marjon J. A. M. Verstegen, Peter H. L. Krijger, Karima Hajo, Marieke Simonis, Agata Rakszewska, Max van Min, Daphne de Jong, Bauke Ylstra, Harma Feitsma, Erik Splinter, Wouter de Laat
Published 2021-06-01

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

by Walderik W. Zomerman, Sabine L.A. Plasschaert, Siobhan Conroy, Frank J. Scherpen, Tiny G.J. Meeuwsen-de Boer, Harm J. Lourens, Sergi Guerrero Llobet, Marlinde J. Smit, Lorian Slagter-Menkema, Annika Seitz, Corrie E.M. Gidding, Esther Hulleman, Pieter Wesseling, Lisethe Meijer, Leon C. van Kempen, Anke van den Berg, Daniël O. Warmerdam, Frank A.E. Kruyt, Floris Foijer, Marcel A.T.M. van Vugt, Wilfred F.A. den Dunnen, Eelco W. Hoving, Victor Guryev, Eveline S.J.M. de Bont, Sophia W.M. Bruggeman
Published 2018-03-01