Push It to the Limit: Identification of Novel Amino Acid Changes on the Acetolactate Synthase Enzyme of Rice That Putatively Confer High Level of Tolerance to Different Imidazolino...

by Giseli Buffon, Thainá Inês Lamb, Mara Cristina Barbosa Lopes, Raul Antonio Sperotto, Raul Antonio Sperotto, Luís Fernando Saraiva Macedo Timmers, Luís Fernando Saraiva Macedo Timmers
Published 2020-02-01

The importance of the quaternary structure to represent conformational ensembles of the major Mycobacterium tuberculosis drug target

by Renata Fioravanti Tarabini, Luís Fernando Saraiva Macedo Timmers, Carlos Eduardo Sequeiros-Borja, Osmar Norberto de Souza
Published 2019-09-01

A Special View of What Was Almost Forgotten: p38δ MAPK

by Débora Bublitz Anton, Rodrigo Gay Ducati, Luís Fernando Saraiva Macedo Timmers, Stefan Laufer, Márcia Inês Goettert
Published 2021-04-01

Molecular Characterisation of Soybean Osmotins and Their Involvement in Drought Stress Response

by Giulia Ramos Faillace, Paula Bacaicoa Caruso, Luis Fernando Saraiva Macedo Timmers, Luis Fernando Saraiva Macedo Timmers, Débora Favero, Frank Lino Guzman, Ciliana Rechenmacher, Luisa Abruzzi de Oliveira-Busatto, Osmar Norberto de Souza, Osmar Norberto de Souza, Christian Bredemeier, Maria Helena Bodanese-Zanettini
Published 2021-06-01

Neuropsychiatric Disorders and COVID-19: What We Know So Far

by Fernanda Majolo, Guilherme Liberato da Silva, Lucas Vieira, Cetin Anli, Luís Fernando Saraiva Macedo Timmers, Stefan Laufer, Márcia Inês Goettert
Published 2021-09-01

Does Angiotensin II Peak in Response to SARS-CoV-2?

by Léder Leal Xavier, Paula Fernanda Ribas Neves, Lisiê Valeria Paz, Laura Tartari Neves, Pamela Brambilla Bagatini, Luís Fernando Saraiva Macedo Timmers, Alberto Antônio Rasia-Filho, Régis Gemerasca Mestriner, Andrea Wieck
Published 2021-01-01

A Network Flow Approach to Predict Protein Targets and Flavonoid Backbones to Treat Respiratory Syncytial Virus Infection

by José Eduardo Vargas, Renato Puga, Joice de Faria Poloni, Luis Fernando Saraiva Macedo Timmers, Barbara Nery Porto, Osmar Norberto de Souza, Diego Bonatto, Paulo Márcio Condessa Pitrez, Renato Tetelbom Stein
Published 2015-01-01

8-Mercaptoguanine-based inhibitors of Mycobacterium tuberculosis dihydroneopterin aldolase: synthesis, in vitro inhibition and docking studies

by Alexia de Matos Czeczot, Candida Deves Roth, Rodrigo Gay Ducati, Kenia Pissinate, Raoní Scheibler Rambo, Luís Fernando Saraiva Macedo Timmers, Bruno Lopes Abbadi, Fernanda Souza Macchi, Víctor Zajaczkowski Pestana, Luiz Augusto Basso, Pablo Machado, Cristiano Valim Bizarro
Published 2021-01-01

Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function

by Lilian Cruz, Bence György, Pike See Cheah, Benjamin P. Kleinstiver, William A. Eimer, Sara P. Garcia, Nutan Sharma, Laurie J. Ozelius, D. Cristopher Bragg, J. Keith Joung, Osmar Norberto de Souza, Luis Fernando Saraiva Macedo Timmers, Xandra O. Breakefield
Published 2020-09-01

SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions

by Luis Fernando Saraiva Macedo Timmers, Julia Vasconcellos Peixoto, Rodrigo Gay Ducati, José Fernando Ruggiero Bachega, Leandro de Mattos Pereira, Rafael Andrade Caceres, Fernanda Majolo, Guilherme Liberato da Silva, Débora Bublitz Anton, Odir Antônio Dellagostin, João Antônio Pegas Henriques, Léder Leal Xavier, Márcia Inês Goettert, Stefan Laufer
Published 2021-06-01