Vaccination with <i>Schistosoma mansoni</i> Cholinesterases Reduces the Parasite Burden and Egg Viability in a Mouse Model of Schistosomiasis

by Bemnet A. Tedla, Darren Pickering, Luke Becker, Alex Loukas, Mark S. Pearson
Published 2020-04-01

Metabolomes and Lipidomes of the Infective Stages of the Gastrointestinal nematodes, <i>Nippostrongylus brasiliensis</i> and <i>Trichuris muris</i>

by Karma Yeshi, Darren J. Creek, Dovile Anderson, Edita Ritmejerytė, Luke Becker, Alex Loukas, Phurpa Wangchuk
Published 2020-11-01

Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signalling and drug detoxification and are essential for parasite survival.

by Bemnet A Tedla, Javier Sotillo, Darren Pickering, Ramon M Eichenberger, Stephanie Ryan, Luke Becker, Alex Loukas, Mark S Pearson
Published 2019-12-01

Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris.

by Phurpa Wangchuk, Mark S Pearson, Paul R Giacomin, Luke Becker, Javier Sotillo, Darren Pickering, Michael J Smout, Alex Loukas
Published 2016-08-01

Oral Peptide Vaccine against Hookworm Infection: Correlation of Antibody Titers with Protective Efficacy

by Ahmed O. Shalash, Luke Becker, Jieru Yang, Paul Giacomin, Mark Pearson, Waleed M. Hussein, Alex Loukas, Mariusz Skwarczynski, Istvan Toth
Published 2021-09-01

Seroprevalence and spatial epidemiology of Lymphatic Filariasis in American Samoa after successful mass drug administration.

by Colleen L Lau, Kimberly Y Won, Luke Becker, Ricardo J Soares Magalhaes, Saipale Fuimaono, Wayne Melrose, Patrick J Lammie, Patricia M Graves
Published 2014-01-01

<i>Schistosoma Haematobium</i> Extracellular Vesicle Proteins Confer Protection in a Heterologous Model of Schistosomiasis

by Gebeyaw G. Mekonnen, Bemnet A. Tedla, Darren Pickering, Luke Becker, Lei Wang, Bin Zhan, Maria Elena Bottazzi, Alex Loukas, Javier Sotillo, Mark S. Pearson
Published 2020-07-01

Lymphatic Filariasis Increases Tissue Compressibility and Extracellular Fluid in Lower Limbs of Asymptomatic Young People in Central Myanmar

by Janet Douglass, Patricia Graves, Daniel Lindsay, Luke Becker, Maureen Roineau, Jesse Masson, Ni Ni Aye, San San Win, Tint Wai, Yi Yi Win, Susan Gordon
Published 2017-09-01

In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination.

by Javier Sotillo, Mark S Pearson, Luke Becker, Gebeyaw G Mekonnen, Abena S Amoah, Govert van Dam, Paul L A M Corstjens, Janice Murray, Takafira Mduluza, Francisca Mutapi, Alex Loukas
Published 2019-05-01

Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.

by Madhu K Sundaraneedi, Bemnet A Tedla, Ramon M Eichenberger, Luke Becker, Darren Pickering, Michael J Smout, Siji Rajan, Phurpa Wangchuk, F Richard Keene, Alex Loukas, J Grant Collins, Mark S Pearson
Published 2017-12-01

Immunomics-Guided Antigen Discovery for Praziquantel-Induced Vaccination in Urogenital Human Schistosomiasis

by Mark S. Pearson, Bemnet A. Tedla, Luke Becker, Rie Nakajima, Al Jasinskas, Takafira Mduluza, Takafira Mduluza, Francisca Mutapi, Francisca Mutapi, Claude Oeuvray, Beatrice Greco, Javier Sotillo, Javier Sotillo, Philip L. Felgner, Alex Loukas
Published 2021-05-01