Editing of the Human <i>TRIM5</i> Gene Decreases the Permissiveness of Jurkat T Lymphocytic Cells to HIV-1

by Kevin Désaulniers, Levine Ortiz, Caroline Dufour, Alix Claudel, Mélodie B. Plourde, Natacha Merindol, Lionel Berthoux
Published 2020-06-01

Editing of the TRIM5 Gene Decreases the Permissiveness of Human T Lymphocytic Cells to HIV-1

by Kevin Désaulniers, Levine Ortiz, Caroline Dufour, Alix Claudel, Mélodie B. Plourde, Natacha Merindol, Lionel Berthoux
Published 2021-12-01

Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1.

by Caroline Dufour, Alix Claudel, Nicolas Joubarne, Natacha Merindol, Tara Maisonnet, Nasser Masroori, Mélodie B Plourde, Lionel Berthoux
Published 2018-01-01

A putative SUMO interacting motif in the B30.2/SPRY domain of rhesus macaque TRIM5α important for NF-κB/AP-1 signaling and HIV-1 restriction

by Marie-Édith Nepveu-Traversy, Ann Demogines, Thomas Fricke, Mélodie B. Plourde, Kathleen Riopel, Maxime Veillette, Felipe Diaz-Griffero, Sara L. Sawyer, Lionel Berthoux
Published 2016-01-01

The Fungal Effector Mlp37347 Alters Plasmodesmata Fluxes and Enhances Susceptibility to Pathogen

by Md. Saifur Rahman, Mst Hur Madina, Mélodie B. Plourde, Karen Cristine Gonçalves dos Santos, Xiaoqiang Huang, Yang Zhang, Jean-François Laliberté, Hugo Germain
Published 2021-06-01

HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state.

by Natacha Merindol, Mohamed El-Far, Mohamed Sylla, Nasser Masroori, Caroline Dufour, Jia-Xin Li, Pearl Cherry, Mélodie B Plourde, Cécile Tremblay, Lionel Berthoux
Published 2018-11-01

Gene Knockout Shows That PML (TRIM19) Does Not Restrict the Early Stages of HIV-1 Infection in Human Cell Lines

by Nasser Masroori, Pearl Cherry, Natacha Merindol, Jia-xin Li, Caroline Dufour, Lina Poulain, Mélodie B. Plourde, Lionel Berthoux, Carolyn B. Coyne, Christopher Aiken, Beatriz Pacheco
Published 2017-06-01