Id2 deletion attenuates Apc-deficient ileal tumor formation

by Kyoko Biyajima, Fumihiko Kakizaki, Xiaodong Shen, Kentaro Mori, Manabu Sugai, M. Mark Taketo, Yoshifumi Yokota
Published 2015-08-01

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine

by Yu Muta, Yoshihisa Fujita, Kenta Sumiyama, Atsuro Sakurai, M. Mark Taketo, Tsutomu Chiba, Hiroshi Seno, Kazuhiro Aoki, Michiyuki Matsuda, Masamichi Imajo
Published 2018-06-01

Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy

by Takehito Yamamoto, Hiroyuki Miyoshi, Fumihiko Kakizaki, Hisatsugu Maekawa, Tadayoshi Yamaura, Tomonori Morimoto, Toshiro Katayama, Kenji Kawada, Yoshiharu Sakai, M. Mark Taketo
Published 2020-07-01

An interdigit signalling centre instructs coordinate phalanx-joint formation governed by 5′Hoxd–Gli3 antagonism

by Bau-Lin Huang, Anna Trofka, Aki Furusawa, Jacqueline L. Norrie, Adam H. Rabinowitz, Steven A. Vokes, M. Mark Taketo, Jozsef Zakany, Susan Mackem
Published 2016-10-01

The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

by Takeshi Ito, Yohei Kawai, Yutaka Yasui, Shoichi Iriguchi, Atsutaka Minagawa, Tomoko Ishii, Hiroyuki Miyoshi, M. Mark Taketo, Kenji Kawada, Kazutaka Obama, Yoshiharu Sakai, Shin Kaneko
Published 2021-06-01

Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice

by Fabienne Benz, Viraya Wichitnaowarat, Martin Lehmann, Raoul FV Germano, Diana Mihova, Jadranka Macas, Ralf H Adams, M Mark Taketo, Karl-Heinz Plate, Sylvaine Guérit, Benoit Vanhollebeke, Stefan Liebner
Published 2019-04-01

Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate

by Kyle A. Wegner, Vatsal Mehta, Jeanette A. Johansson, Brett R. Mueller, Kimberly P. Keil, Lisa L. Abler, Paul C. Marker, M. Mark Taketo, Denis J. Headon, Chad M. Vezina
Published 2019-03-01

A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease

by Qi Sun, Wendy Lee, Yasuaki Mohri, Makoto Takeo, Chae Ho Lim, Xiaowei Xu, Peggy Myung, Radhika P. Atit, M. Mark Taketo, Rana S. Moubarak, Markus Schober, Iman Osman, Denise L. Gay, Dieter Saur, Emi K. Nishimura, Mayumi Ito
Published 2019-11-01

Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

by Chae Ho Lim, Qi Sun, Karan Ratti, Soung-Hoon Lee, Ying Zheng, Makoto Takeo, Wendy Lee, Piul Rabbani, Maksim V. Plikus, Jason E. Cain, David H. Wang, D. Neil Watkins, Sarah Millar, M. Mark Taketo, Peggy Myung, George Cotsarelis, Mayumi Ito
Published 2018-11-01

IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells

by Serkan I. Göktuna, Ozge Canli, Julia Bollrath, Alexander A. Fingerle, David Horst, Michaela A. Diamanti, Charles Pallangyo, Moritz Bennecke, Tim Nebelsiek, Arun K. Mankan, Roland Lang, David Artis, Yinling Hu, Thomas Patzelt, Jürgen Ruland, Thomas Kirchner, M. Mark Taketo, Alain Chariot, Melek C. Arkan, Florian R. Greten
Published 2014-06-01