Imbalance of Circulating Th17 and Regulatory T Cells in Alzheimer’s Disease: A Case Control Study

by Timo Jan Oberstein, Lava Taha, Philipp Spitzer, Janina Hellstern, Martin Herrmann, Johannes Kornhuber, Juan Manuel Maler
Published 2018-06-01

Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines

by Philipp Spitzer, Matthias Walter, Caroline Göth, Timo Jan Oberstein, Philipp Linning, Hans-Joachim Knölker, Johannes Kornhuber, Juan Manuel Maler
Published 2020-09-01

Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer’s disease

by Piotr Lewczuk, Natalia Ermann, Ulf Andreasson, Christian Schultheis, Jana Podhorna, Philipp Spitzer, Juan Manuel Maler, Johannes Kornhuber, Kaj Blennow, Henrik Zetterberg
Published 2018-07-01

Cerebrospinal Fluid of Patients With Alzheimer’s Disease Contains Increased Percentages of Synaptophysin-Bearing Microvesicles

by Janine Utz, Judith Berner, Luis Enrique Muñoz, Luis Enrique Muñoz, Timo Jan Oberstein, Johannes Kornhuber, Martin Herrmann, Martin Herrmann, Juan Manuel Maler, Philipp Spitzer
Published 2021-07-01

DSC Brain Perfusion Using Advanced Deconvolution Models in the Diagnostic Work-up of Dementia and Mild Cognitive Impairment: A Semiquantitative Comparison with HMPAO-SPECT-Brain Pe...

by Manuel A. Schmidt, Tobias Engelhorn, Stefan Lang, Hannes Luecking, Philip Hoelter, Kilian Froehlich, Philipp Ritt, Juan Manuel Maler, Torsten Kuwert, Johannes Kornhuber, Arnd Doerfler
Published 2020-06-01

Depression, Anxiety, Resilience and Coping Pre and Post Kidney Transplantation - Initial Findings from the Psychiatric Impairments in Kidney Transplantation (PI-KT)-Study.

by Helge H Müller, Matthias Englbrecht, Michael S Wiesener, Stephanie Titze, Katharina Heller, Teja W Groemer, Georg Schett, Kai-Uwe Eckardt, Johannes Kornhuber, Juan Manuel Maler
Published 2015-01-01

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides

by Timo Jan Oberstein, Philipp Spitzer, Hans-Wolfgang Klafki, Philipp Linning, Florian Neff, Hans-Joachim Knölker, Piotr Lewczuk, Jens Wiltfang, Johannes Kornhuber, Juan Manuel Maler
Published 2015-01-01

The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes

by Timo Jan Oberstein, Janine Utz, Philipp Spitzer, Hans Wolfgang Klafki, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Piotr Lewczuk, Piotr Lewczuk, Johannes Kornhuber, Juan Manuel Maler
Published 2021-01-01

cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases

by Philipp Spitzer, Hans Wolfgang Klafki, Kaj Blennow, Luc Buée, Hermann Esselmann, Sanna-Kaisa Herruka, Connie Jimenez, Peter Klivenyi, Piotr Lewczuk, Juan Manuel Maler, Katrin Markus, Helmut E. Meyer, Chris Morris, Thorsten Müller, Markus Otto, Lucilla Parnetti, Hilkka Soininen, Susanna Schraen, Charlotte Teunissen, Laszlo Vecsei, Henrik Zetterberg, Jens Wiltfang
Published 2010-01-01

Atrophy in the Thalamus But Not Cerebellum Is Specific for C9orf72 FTD and ALS Patients – An Atlas-Based Volumetric MRI Study

by Sonja Schönecker, Christiane Neuhofer, Markus Otto, Albert Ludolph, Jan Kassubek, Bernhard Landwehrmeyer, Sarah Anderl-Straub, Elisa Semler, Janine Diehl-Schmid, Catharina Prix, Christian Vollmar, Juan Fortea, Deutsches FTLD-Konsortium, Hans-Jürgen Huppertz, Thomas Arzberger, Dieter Edbauer, Dieter Edbauer, Dieter Edbauer, Berend Feddersen, Marianne Dieterich, Marianne Dieterich, Marianne Dieterich, Matthias L. Schroeter, Matthias L. Schroeter, Alexander E. Volk, Klaus Fließbach, Klaus Fließbach, Anja Schneider, Anja Schneider, Johannes Kornhuber, Manuel Maler, Johannes Prudlo, Johannes Prudlo, Holger Jahn, Holger Jahn, Tobias Boeckh-Behrens, Adrian Danek, Thomas Klopstock, Thomas Klopstock, Thomas Klopstock, Johannes Levin, Johannes Levin, Carola Roßmeier, Franziska Albrecht, Katharina Schümberg, Sandrine Bisenius
Published 2018-03-01