CD28 between tolerance and autoimmunity: the side effects of animal models [version 1; referees: 2 approved]

by Nicla Porciello, Martina Kunkl, Loretta Tuosto
Published 2018-05-01

T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis

by Martina Kunkl, Simone Frascolla, Carola Amormino, Elisabetta Volpe, Loretta Tuosto
Published 2020-02-01

Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

by Martina Kunkl, Martina Kunkl, Carola Amormino, Carola Amormino, Silvana Caristi, Silvana Caristi, Valentina Tedeschi, Maria Teresa Fiorillo, Revital Levy, Andrey Popugailo, Raymond Kaempfer, Loretta Tuosto, Loretta Tuosto
Published 2021-08-01

CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes

by Martina Kunkl, Martina Kunkl, Carola Amormino, Carola Amormino, Simone Frascolla, Simone Frascolla, Manolo Sambucci, Marco De Bardi, Silvana Caristi, Stefano Arcieri, Luca Battistini, Loretta Tuosto, Loretta Tuosto
Published 2020-10-01

CD28 Autonomous Signaling Up-Regulates C-Myc Expression and Promotes Glycolysis Enabling Inflammatory T Cell Responses in Multiple Sclerosis

by Martina Kunkl, Manolo Sambucci, Serena Ruggieri, Carola Amormino, Carla Tortorella, Claudio Gasperini, Luca Battistini, Loretta Tuosto
Published 2019-06-01

CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter

by Martina Kunkl, Marta Mastrogiovanni, Marta Mastrogiovanni, Nicla Porciello, Silvana Caristi, Emanuele Monteleone, Stefano Arcieri, Loretta Tuosto
Published 2019-04-01

ISA-2011B, a Phosphatidylinositol 4-Phosphate 5-Kinase α Inhibitor, Impairs CD28-Dependent Costimulatory and Pro-inflammatory Signals in Human T Lymphocytes

by Loretta Tuosto, Martina Kunkl, Nicla Porciello, Marta Mastrogiovanni, Cristina Capuano, Federica Lucantoni, Chiara Moretti, Jenny L. Persson, Jenny L. Persson, Ricciarda Galandrini, Raffaella Buzzetti
Published 2017-04-01

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

by Nicla Porciello, Paola Grazioli, Antonio F. Campese, Martina Kunkl, Silvana Caristi, Marta Mastrogiovanni, Michela Muscolini, Francesca Spadaro, Cédric Favre, Jacques A. Nunès, Aldo Borroto, Balbino Alarcon, Isabella Screpanti, Loretta Tuosto
Published 2018-03-01