Calcium Dyshomeostasis and Lysosomal Ca²⁺ Dysfunction in Amyotrophic Lateral Sclerosis

by Valentina Tedeschi, Tiziana Petrozziello, Agnese Secondo
Published 2019-10-01

HLA Class I or Class II and Disease Association: Catch the Difference If You Can

by Maria Teresa Fiorillo, Fabiana Paladini, Valentina Tedeschi, Rosa Sorrentino
Published 2017-11-01

The Multifaceted Nature of Aminopeptidases ERAP1, ERAP2, and LNPEP: From Evolution to Disease

by Fabiana Paladini, Maria Teresa Fiorillo, Valentina Tedeschi, Benedetta Mattorre, Rosa Sorrentino
Published 2020-07-01

Ankylosing Spondylitis: A Trade Off of HLA-B27, ERAP, and Pathogen Interconnections? Focus on Sardinia

by Fabiana Paladini, Maria Teresa Fiorillo, Valentina Tedeschi, Alberto Cauli, Alessandro Mathieu, Rosa Sorrentino
Published 2019-01-01

The Impact of the ‘Mis-Peptidome’ on HLA Class I-Mediated Diseases: Contribution of ERAP1 and ERAP2 and Effects on the Immune Response

by Valentina Tedeschi, Giorgia Paldino, Fabiana Paladini, Benedetta Mattorre, Loretta Tuosto, Rosa Sorrentino, Maria Teresa Fiorillo
Published 2020-12-01

The Ankylosing Spondylitis-Associated HLA-B*2705 Presents a B*0702-Restricted EBV Epitope and Sustains the Clonal Amplification of Cytotoxic T Cells in Patients

by Valentina Tedeschi, Carolina Vitulano, Alberto Cauli, Fabiana Paladini, Matteo Piga, Alessandro Mathieu, Rosa Sorrentino, Maria Teresa Fiorillo
Published 2016-05-01

The Antioxidant Activity of Limonene Counteracts Neurotoxicity Triggered byAβ_1-42 Oligomers in Primary Cortical Neurons

by Ilaria Piccialli, Valentina Tedeschi, Lucia Caputo, Giuseppe Amato, Laura De Martino, Vincenzo De Feo, Agnese Secondo, Anna Pannaccione
Published 2021-06-01

The <i>Anemonia sulcata</i> Toxin BDS-I Protects Astrocytes Exposed to Aβ_1–42 Oligomers by Restoring [Ca²⁺]_i Transients and ER Ca²⁺ Sign...

by Ilaria Piccialli, Valentina Tedeschi, Francesca Boscia, Roselia Ciccone, Antonella Casamassa, Valeria de Rosa, Paolo Grieco, Agnese Secondo, Anna Pannaccione
Published 2021-12-01

Unusual Placement of an EBV Epitope into the Groove of the Ankylosing Spondylitis-Associated HLA-B27 Allele Allows CD8+ T Cell Activation

by Valentina Tedeschi, Josephine Alba, Fabiana Paladini, Marino Paroli, Alberto Cauli, Alessandro Mathieu, Rosa Sorrentino, Marco D’Abramo, Maria Teresa Fiorillo
Published 2019-06-01

Interaction pattern of Arg 62 in the A-pocket of differentially disease-associated HLA-B27 subtypes suggests distinct TCR binding modes.

by Elisa Nurzia, Daniele Narzi, Alberto Cauli, Alessandro Mathieu, Valentina Tedeschi, Silvana Caristi, Rosa Sorrentino, Rainer A Böckmann, Maria Teresa Fiorillo
Published 2012-01-01

Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells

by Ahmed Mahal, Stefano D’Errico, Nicola Borbone, Brunella Pinto, Agnese Secondo, Valeria Costantino, Valentina Tedeschi, Giorgia Oliviero, Vincenzo Piccialli, Gennaro Piccialli
Published 2015-12-01

Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes

by Mariarosaria Cammarota, Valeria de Rosa, Anna Pannaccione, Agnese Secondo, Valentina Tedeschi, Ilaria Piccialli, Ferdinando Fiorino, Beatrice Severino, Lucio Annunziato, Francesca Boscia
Published 2021-11-01

Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

by Martina Kunkl, Martina Kunkl, Carola Amormino, Carola Amormino, Silvana Caristi, Silvana Caristi, Valentina Tedeschi, Maria Teresa Fiorillo, Revital Levy, Andrey Popugailo, Raymond Kaempfer, Loretta Tuosto, Loretta Tuosto
Published 2021-08-01

Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model

by Serenella Anzilotti, Valeria Valsecchi, Paola Brancaccio, Natascia Guida, Giusy Laudati, Valentina Tedeschi, Tiziana Petrozziello, Francesco Frecentese, Elisa Magli, Brenda Hassler, Ornella Cuomo, Luigi Formisano, Agnese Secondo, Lucio Annunziato, Giuseppe Pignataro
Published 2021-11-01