IDO1-Targeted Therapy Does Not Control Disease Development in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia

by Selcen Öztürk, Verena Kalter, Philipp M. Roessner, Murat Sunbul, Martina Seiffert
Published 2021-04-01

Isolation, Structural Analyses and Biological Activity Assays against Chronic Lymphocytic Leukemia of Two Novel Cytochalasins — Sclerotionigrin A and B

by Lene M. Petersen, Tanja T. Bladt, Claudia Dürr, Martina Seiffert, Jens C. Frisvad, Charlotte H. Gotfredsen, Thomas O. Larsen
Published 2014-07-01

Optimized Protocol for Isolation of Small Extracellular Vesicles from Human and Murine Lymphoid Tissues

by Marie Bordas, Géraldine Genard, Sibylle Ohl, Michelle Nessling, Karsten Richter, Tobias Roider, Sascha Dietrich, Kendra K. Maaß, Martina Seiffert
Published 2020-08-01

Bio-Activity and Dereplication-Based Discovery of Ophiobolins and Other Fungal Secondary Metabolites Targeting Leukemia Cells

by Tanja Thorskov Bladt, Claudia Dürr, Peter Boldsen Knudsen, Sara Kildgaard, Jens Christian Frisvad, Charlotte Held Gotfredsen, Martina Seiffert, Thomas Ostenfeld Larsen
Published 2013-11-01

Phosphoinositide 3-Kinase Signaling in the Tumor Microenvironment: What Do We Need to Consider When Treating Chronic Lymphocytic Leukemia With PI3K Inhibitors?

by Ebru Aydin, Ebru Aydin, Sebastian Faehling, Sebastian Faehling, Mariam Saleh, Mariam Saleh, Laura Llaó Cid, Laura Llaó Cid, Martina Seiffert, Philipp M. Roessner
Published 2021-01-01

Dissecting the Prognostic Significance and Functional Role of Progranulin in Chronic Lymphocytic Leukemia

by Lena Schulze-Edinghausen, Claudia Dürr, Selcen Öztürk, Manuela Zucknick, Axel Benner, Verena Kalter, Sibylle Ohl, Viola Close, Patrick Wuchter, Stephan Stilgenbauer, Peter Lichter, Martina Seiffert
Published 2019-06-01

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

by Justyna A. Wierzbinska, Reka Toth, Naveed Ishaque, Karsten Rippe, Jan-Philipp Mallm, Lara C. Klett, Daniel Mertens, Thorsten Zenz, Thomas Hielscher, Marc Seifert, Ralf Küppers, Yassen Assenov, Pavlo Lutsik, Stephan Stilgenbauer, Philipp M. Roessner, Martina Seiffert, John Byrd, Christopher C. Oakes, Christoph Plass, Daniel B. Lipka
Published 2020-03-01