Application of Adoptive T-Cell Therapy Using Tumor Antigen-Specific T-Cell Receptor Gene Transfer for the Treatment of Human Leukemia

by Toshiki Ochi, Hiroshi Fujiwara, Masaki Yasukawa
Published 2010-01-01

Usefulness of Low-Dose Splenic Irradiation prior to Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Elderly Patients with Myelofibrosis

by Etsuko Matsubara, Jun Yamanouchi, Riko Kitazawa, Taichi Azuma, Hiroshi Fujiwara, Takaaki Hato, Masaki Yasukawa
Published 2016-01-01

The Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells.

by Toshiaki Yasuoka, Makoto Kuwahara, Takeshi Yamada, Saho Maruyama, Junpei Suzuki, Masaru Taniguchi, Masaki Yasukawa, Masakatsu Yamashita
Published 2016-01-01

A Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Receptor for Anti-Leukaemia Adoptive Immunotherapy.

by Nicholas Paul Casey, Hiroshi Fujiwara, Kazushi Tanimoto, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Masaki Yasukawa
Published 2016-01-01

A Promising Vector for TCR Gene Therapy: Differential Effect of siRNA, 2A Peptide, and Disulfide Bond on the Introduced TCR Expression

by Sachiko Okamoto, Yasunori Amaishi, Yumi Goto, Hiroaki Ikeda, Hiroshi Fujiwara, Kiyotaka Kuzushima, Masaki Yasukawa, Hiroshi Shiku, Junichi Mineno
Published 2012-01-01

A single-chain antibody generation system yielding CAR-T cells with superior antitumor function

by Toshiki Ochi, Masaki Maruta, Kazushi Tanimoto, Fumitake Kondo, Toshihiro Yamamoto, Mie Kurata, Hiroshi Fujiwara, Junya Masumoto, Katsuto Takenaka, Masaki Yasukawa
Published 2021-03-01

HLA class I binding of HBZ determines outcome in HTLV-1 infection.

by Aidan Macnamara, Aileen Rowan, Silva Hilburn, Ulrich Kadolsky, Hiroshi Fujiwara, Koichiro Suemori, Masaki Yasukawa, Graham Taylor, Charles R M Bangham, Becca Asquith
Published 2010-09-01

Co-introduced functional CCR2 potentiates in vivo anti-lung cancer functionality mediated by T cells double gene-modified to express WT1-specific T-cell receptor.

by Hiroaki Asai, Hiroshi Fujiwara, Jun An, Toshiki Ochi, Yukihiro Miyazaki, Kozo Nagai, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Hirofumi Inoue, Masaki Yasukawa
Published 2013-01-01

The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation

by Junpei Suzuki, Takeshi Yamada, Kazuki Inoue, Shogo Nabe, Makoto Kuwahara, Nobuaki Takemori, Ayako Takemori, Seiji Matsuda, Makoto Kanoh, Yuuki Imai, Masaki Yasukawa, Masakatsu Yamashita
Published 2018-08-01

Abnormal behaviors and developmental disorder of hippocampus in zinc finger protein 521 (ZFP521) mutant mice.

by Nobutaka Ohkubo, Etsuko Matsubara, Jun Yamanouchi, Rie Akazawa, Mamoru Aoto, Yoji Suzuki, Ikuya Sakai, Takaya Abe, Hiroshi Kiyonari, Seiji Matsuda, Masaki Yasukawa, Noriaki Mitsuda
Published 2014-01-01

Analysis of Clinical Factors and Mortality in Diffuse Large B-cell Lymphoma Patients Over or Under 80 Years of Age

by Shinji Hasebe, Keiko Tanaka, Yoshihiro Miyake, Hiroaki Asai, Kazuto Takeuchi, Tomomi Fujii, Hitoshi Kawazoe, Kazushi Tanimoto, Jun Yamanouchi, Taichi Azuma, Masaki Yasukawa, Yoshihiro Yakushijin
Published 2018-06-01

Novel Autoantigens Associated with Lupus Nephritis.

by Sachiko Onishi, Endy Adnan, Jun Ishizaki, Tatsuhiko Miyazaki, Yuki Tanaka, Takuya Matsumoto, Koichiro Suemori, Masachika Shudou, Takafumi Okura, Hiroyuki Takeda, Tatsuya Sawasaki, Masaki Yasukawa, Hitoshi Hasegawa
Published 2015-01-01

Subtypes of familial hemophagocytic lymphohistiocytosis in Japan based on genetic and functional analyses of cytotoxic T lymphocytes.

by Kozo Nagai, Ken Yamamoto, Hiroshi Fujiwara, Jun An, Toshiki Ochi, Koichiro Suemori, Takahiro Yasumi, Hisamichi Tauchi, Katsuyoshi Koh, Maho Sato, Akira Morimoto, Toshio Heike, Eiichi Ishii, Masaki Yasukawa
Published 2010-01-01

Bach2–Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop

by Makoto Kuwahara, Wataru Ise, Mizuki Ochi, Junpei Suzuki, Kohei Kometani, Saho Maruyama, Maya Izumoto, Akira Matsumoto, Nobuaki Takemori, Ayako Takemori, Kenta Shinoda, Toshinori Nakayama, Osamu Ohara, Masaki Yasukawa, Tatsuya Sawasaki, Tomohiro Kurosaki, Masakatsu Yamashita
Published 2016-09-01

A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

by Shoichi Iriguchi, Yutaka Yasui, Yohei Kawai, Suguru Arima, Mihoko Kunitomo, Takayuki Sato, Tatsuki Ueda, Atsutaka Minagawa, Yuta Mishima, Nariaki Yanagawa, Yuji Baba, Yasuyuki Miyake, Kazuhide Nakayama, Maiko Takiguchi, Tokuyuki Shinohara, Tetsuya Nakatsura, Masaki Yasukawa, Yoshiaki Kassai, Akira Hayashi, Shin Kaneko
Published 2021-01-01

Cytotoxic T Lymphocytes Regenerated from iPS Cells Have Therapeutic Efficacy in a Patient-Derived Xenograft Solid Tumor Model

by Soki Kashima, Takuya Maeda, Kyoko Masuda, Seiji Nagano, Takamitsu Inoue, Masashi Takeda, Yuka Kono, Takashi Kobayashi, Shigeyoshi Saito, Takahiro Higuchi, Hiroshi Ichise, Yuka Kobayashi, Keiko Iwaisako, Koji Terada, Yasutoshi Agata, Kazuyuki Numakura, Mitsuru Saito, Shintaro Narita, Masaki Yasukawa, Osamu Ogawa, Tomonori Habuchi, Hiroshi Kawamoto
Published 2020-04-01

Targeted proteomics reveals promising biomarkers of disease activity and organ involvement in antineutrophil cytoplasmic antibody-associated vasculitis

by Jun Ishizaki, Ayako Takemori, Koichiro Suemori, Takuya Matsumoto, Yoko Akita, Ken-ei Sada, Yukio Yuzawa, Koichi Amano, Yoshinari Takasaki, Masayoshi Harigai, Yoshihiro Arimura, Hirofumi Makino, Masaki Yasukawa, Nobuaki Takemori, Hitoshi Hasegawa, for the Research Committee of Intractable Vasculitis Syndrome and the Research Committee of Intractable Renal Disease of the Ministry of Health, Labour and Welfare of Japan
Published 2017-09-01

A multicenter non-randomized, uncontrolled single arm trial for evaluation of the efficacy and the safety of the treatment with favipiravir for patients with severe fever with thro...

by Koichiro Suemori, Masayuki Saijo, Atsushi Yamanaka, Daisuke Himeji, Masafumi Kawamura, Takashi Haku, Michihiro Hidaka, Chinatsu Kamikokuryo, Yasuyuki Kakihana, Taichi Azuma, Katsuto Takenaka, Toru Takahashi, Akitsugu Furumoto, Toshiyuki Ishimaru, Masayuki Ishida, Masahiko Kaneko, Norimitsu Kadowaki, Kenichi Ikeda, Shigetoshi Sakabe, Tomohiro Taniguchi, Hiroki Ohge, Takeshi Kurosu, Tomoki Yoshikawa, Masayuki Shimojima, Masaki Yasukawa
Published 2021-02-01