A Gatekeeper Residue for NEDD8-Activating Enzyme Inhibition by MLN4924

by Julia I. Toth, Li Yang, Russell Dahl, Matthew D. Petroski
Published 2012-04-01

Mutations in UBA3 confer resistance to the NEDD8-activating enzyme inhibitor MLN4924 in human leukemic cells.

by G Wei Xu, Julia I Toth, Sara R da Silva, Stacey-Lynn Paiva, Julie L Lukkarila, Rose Hurren, Neil Maclean, Mahadeo A Sukhai, Rabindra N Bhattacharjee, Carolyn A Goard, Bruno Medeiros, Patrick T Gunning, Sirano Dhe-Paganon, Matthew D Petroski, Aaron D Schimmer
Published 2014-01-01