Expression and cellular immunogenicity of a transgenic antigen driven by endogenous poxviral early promoters at their authentic loci in MVA.

by Toritse Orubu, Naif Khalaf Alharbi, Teresa Lambe, Sarah C Gilbert, Matthew G Cottingham
Published 2012-01-01

Correction: Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA)

by Matthew G. Cottingham, Rikke F. Andersen, Alexandra J. Spencer, Saroj Saurya, Julie Furze, Adrian V. S. Hill, Sarah C. Gilbert
Published 2011-01-01

Recombination-mediated genetic engineering of a bacterial artificial chromosome clone of modified vaccinia virus Ankara (MVA).

by Matthew G Cottingham, Rikke F Andersen, Alexandra J Spencer, Saroj Saurya, Julie Furze, Adrian V S Hill, Sarah C Gilbert
Published 2008-02-01

Correction: Recombination-Mediated Genetic Engineering of a Bacterial Artificial Chromosome Clone of Modified Vaccinia virus Ankara (MVA).

by Matthew G. Cottingham, Rikke F. Andersen, Alexandra J. Spencer, Saroj Saurya, Julie Furze, Adrian V. S. Hill, Sarah C. Gilbert
Published 2011-01-01

A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity.

by Matthew D J Dicks, Alexandra J Spencer, Nick J Edwards, Göran Wadell, Kalifa Bojang, Sarah C Gilbert, Adrian V S Hill, Matthew G Cottingham
Published 2012-01-01

Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain.

by Alexandra J Spencer, Matthew G Cottingham, Jennifer A Jenks, Rhea J Longley, Stefania Capone, Stefano Colloca, Antonella Folgori, Riccardo Cortese, Alfredo Nicosia, Migena Bregu, Adrian V S Hill
Published 2014-01-01

4-1BBL enhances CD8+ T cell responses induced by vectored vaccines in mice but fails to improve immunogenicity in rhesus macaques.

by Alexandra J Spencer, Julie Furze, Jared D Honeycutt, Alice Calvert, Saroj Saurya, Stefano Colloca, David H Wyllie, Sarah C Gilbert, Migena Bregu, Matthew G Cottingham, Adrian V S Hill
Published 2014-01-01

T cell responses induced by adenoviral vectored vaccines can be adjuvanted by fusion of antigen to the oligomerization domain of C4b-binding protein.

by Emily K Forbes, Simone C de Cassan, David Llewellyn, Sumi Biswas, Anna L Goodman, Matthew G Cottingham, Carole A Long, Richard J Pleass, Adrian V S Hill, Fergal Hill, Simon J Draper
Published 2012-01-01

Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1.

by Sumi Biswas, Matthew D J Dicks, Carole A Long, Edmond J Remarque, Loredana Siani, Stefano Colloca, Matthew G Cottingham, Anthony A Holder, Sarah C Gilbert, Adrian V S Hill, Simon J Draper
Published 2011-01-01

Fusion of the Mycobacterium tuberculosis antigen 85A to an oligomerization domain enhances its immunogenicity in both mice and non-human primates.

by Alexandra J Spencer, Fergal Hill, Jared D Honeycutt, Matthew G Cottingham, Migena Bregu, Christine S Rollier, Julie Furze, Simon J Draper, Karen C Søgaard, Sarah C Gilbert, David H Wyllie, Adrian V S Hill
Published 2012-01-01