Identification of 34 novel proinflammatory proteins in a genome-wide macrophage functional screen.

by David H Wyllie, Karen C Søgaard, Karen Holland, Xu Yaobo, Migena Bregu, Adrian V S Hill, Endre Kiss-Toth
Published 2012-01-01

Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain.

by Alexandra J Spencer, Matthew G Cottingham, Jennifer A Jenks, Rhea J Longley, Stefania Capone, Stefano Colloca, Antonella Folgori, Riccardo Cortese, Alfredo Nicosia, Migena Bregu, Adrian V S Hill
Published 2014-01-01

4-1BBL enhances CD8+ T cell responses induced by vectored vaccines in mice but fails to improve immunogenicity in rhesus macaques.

by Alexandra J Spencer, Julie Furze, Jared D Honeycutt, Alice Calvert, Saroj Saurya, Stefano Colloca, David H Wyllie, Sarah C Gilbert, Migena Bregu, Matthew G Cottingham, Adrian V S Hill
Published 2014-01-01

Fusion of the Mycobacterium tuberculosis antigen 85A to an oligomerization domain enhances its immunogenicity in both mice and non-human primates.

by Alexandra J Spencer, Fergal Hill, Jared D Honeycutt, Matthew G Cottingham, Migena Bregu, Christine S Rollier, Julie Furze, Simon J Draper, Karen C Søgaard, Sarah C Gilbert, David H Wyllie, Adrian V S Hill
Published 2012-01-01