Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease

by Annie G. Bryant, Miwei Hu, Becky C. Carlyle, Steven E. Arnold, Matthew P. Frosch, Matthew P. Frosch, Sudeshna Das, Bradley T. Hyman, Rachel E. Bennett
Published 2020-09-01

Modeling intracerebral hemorrhage growth and response to anticoagulation.

by Charles H Greenberg, Matthew P Frosch, Joshua N Goldstein, Jonathan Rosand, Steven M Greenberg
Published 2012-01-01

Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain

by Sarah L. DeVos, Bianca T. Corjuc, Derek H. Oakley, Derek H. Oakley, Chloe K. Nobuhara, Riley N. Bannon, Alison Chase, Caitlin Commins, Jose A. Gonzalez, Patrick M. Dooley, Matthew P. Frosch, Matthew P. Frosch, Bradley T. Hyman
Published 2018-04-01

Impairment of visual cortical plasticity by amyloid-beta species

by Christopher M. William, Matthew A. Stern, Xuewei Pei, Lubna Saqran, Margish Ramani, Matthew P. Frosch, Bradley T. Hyman
Published 2021-07-01

Effects of gender on nigral gene expression and parkinson disease

by Ippolita Cantuti-Castelvetri, Christine Keller-McGandy, Bérengère Bouzou, Georgios Asteris, Timothy W. Clark, Matthew P. Frosch, David G. Standaert
Published 2007-06-01

An Ultra-High Speed Whole Slide Image Viewing System

by Yukako Yagi, Shigeatsu Yoshioka, Hiroshi Kyusojin, Maristela Onozato, Yoichi Mizutani, Kiyoshi Osato, Hiroaki Yada, Eugene J. Mark, Matthew P. Frosch, David N. Louis
Published 2012-01-01

Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue

by Cinthya Aguero, Maeva Dhaynaut, Marc D. Normandin, Ana C. Amaral, Nicolas J. Guehl, Ramesh Neelamegam, Marta Marquie, Keith A. Johnson, Georges El Fakhri, Matthew P. Frosch, Teresa Gomez-Isla
Published 2019-03-01

Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

by Monica Garcia-Alloza, Elissa M. Robbins, Sandy X. Zhang-Nunes, Susan M. Purcell, Rebecca A. Betensky, Susan Raju, Claudia Prada, Steven M. Greenberg, Brian J. Bacskai, Matthew P. Frosch
Published 2006-12-01

Different tau species lead to heterogeneous tau pathology propagation and misfolding

by Simon Dujardin, Séverine Bégard, Raphaëlle Caillierez, Cédrick Lachaud, Sébastien Carrier, Sarah Lieger, Jose A. Gonzalez, Vincent Deramecourt, Nicole Déglon, Claude-Alain Maurage, Matthew P. Frosch, Bradley T. Hyman, Morvane Colin, Luc Buée
Published 2018-11-01

An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease

by Ming Jin, Brian O’Nuallain, Wei Hong, Justin Boyd, Valentina N. Lagomarsino, Tiernan T. O’Malley, Wen Liu, Charles R. Vanderburg, Matthew P. Frosch, Tracy Young-Pearse, Dennis J. Selkoe, Dominic M. Walsh
Published 2018-07-01

Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation

by Ana Claudia Amaral, Beatriz G. Perez-Nievas, Michael Siao Tick Chong, Alicia Gonzalez-Martinez, Herminia Argente-Escrig, Sara Rubio-Guerra, Caitlin Commins, Serra Muftu, Bahareh Eftekharzadeh, Eloise Hudry, Zhanyun Fan, Prianca Ramanan, Shuko Takeda, Matthew P. Frosch, Susanne Wegmann, Teresa Gomez-Isla
Published 2021-02-01

[18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series

by Marta Marquié, Cinthya Agüero, Ana C. Amaral, Alberto Villarejo-Galende, Prianca Ramanan, Michael Siao Tick Chong, Nil Sáez-Calveras, Rachel E. Bennett, Eline E. Verwer, Sally Ji Who Kim, Maeva Dhaynaut, Victor E. Alvarez, Keith A. Johnson, Ann C. McKee, Matthew P. Frosch, Teresa Gómez-Isla
Published 2019-10-01

Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson’s case

by Marta Marquié, Eline E. Verwer, Avery C. Meltzer, Sally Ji Who Kim, Cinthya Agüero, Jose Gonzalez, Sara J. Makaretz, Michael Siao Tick Chong, Prianca Ramanan, Ana C. Amaral, Marc D. Normandin, Charles R. Vanderburg, Stephen N. Gomperts, Keith A. Johnson, Matthew P. Frosch, Teresa Gómez-Isla
Published 2017-10-01

Distinct cytokine profiles in human brains resilient to Alzheimer's pathology

by Isabel Barroeta-Espar, Laura D. Weinstock, Beatriz G. Perez-Nievas, Avery C. Meltzer, Michael Siao Tick Chong, Ana C. Amaral, Melissa E. Murray, Krista L. Moulder, John C. Morris, Nigel J. Cairns, Joseph E. Parisi, Val J. Lowe, Ronald C. Petersen, Julia Kofler, Milos D. Ikonomovic, Oscar López, William E. Klunk, Richard P. Mayeux, Matthew P. Frosch, Levi B. Wood, Teresa Gomez-Isla
Published 2019-01-01

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.

by Gary W Beecham, Kara Hamilton, Adam C Naj, Eden R Martin, Matt Huentelman, Amanda J Myers, Jason J Corneveaux, John Hardy, Jean-Paul Vonsattel, Steven G Younkin, David A Bennett, Philip L De Jager, Eric B Larson, Paul K Crane, M Ilyas Kamboh, Julia K Kofler, Deborah C Mash, Linda Duque, John R Gilbert, Harry Gwirtsman, Joseph D Buxbaum, Patricia Kramer, Dennis W Dickson, Lindsay A Farrer, Matthew P Frosch, Bernardino Ghetti, Jonathan L Haines, Bradley T Hyman, Walter A Kukull, Richard P Mayeux, Margaret A Pericak-Vance, Julie A Schneider, John Q Trojanowski, Eric M Reiman, Alzheimer's Disease Genetics Consortium (ADGC), Gerard D Schellenberg, Thomas J Montine
Published 2014-09-01

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

by Eric M. Reiman, Joseph F. Arboleda-Velasquez, Yakeel T. Quiroz, Matthew J. Huentelman, Thomas G. Beach, Richard J. Caselli, Yinghua Chen, Yi Su, Amanda J. Myers, John Hardy, Jean Paul Vonsattel, Steven G. Younkin, David A. Bennett, Philip L. De Jager, Eric B. Larson, Paul K. Crane, C. Dirk Keene, M. Ilyas Kamboh, Julia K. Kofler, Linda Duque, John R. Gilbert, Harry E. Gwirtsman, Joseph D. Buxbaum, Dennis W. Dickson, Matthew P. Frosch, Bernardino F. Ghetti, Kathryn L. Lunetta, Li-San Wang, Bradley T. Hyman, Walter A. Kukull, Tatiana Foroud, Jonathan L. Haines, Richard P. Mayeux, Margaret A. Pericak-Vance, Julie A. Schneider, John Q. Trojanowski, Lindsay A. Farrer, Gerard D. Schellenberg, Gary W. Beecham, Thomas J. Montine, Gyungah R. Jun, The Alzheimer’s Disease Genetics Consortium
Published 2020-02-01